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MAbPac™ RP LC Columns

Get higher resolution using reversed-phase conditions when separating and characterizing monoclonal antibodies by HPLC and LC/MS.

Manufacturer: thermo fisher scientific  088648

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Catalog No. 08-864-8


Description & Specifications


Max. Temperature <110°C
Max. Pressure 4,000 psi
Packing Material DVB
Particle Size 4µm
Pore Size 1,500 Å
pH 0 - 14
Length (Metric) 50mm
Diameter (Metric) Inner 2.1mm
Column Format Analytical

Use the new Thermo Scientific™ MAbPac™ RP columns for high-performance reversed-phase (RP) HPLC and LC/MS characterization of monoclonal antibodies (mAbs), fragments, variants, antibody drug conjugates (ADCs), PEGylated proteins, and bispecific proteins. These columns have excellent resolution, long column lifetime, and low carry-over. The surface chemistry, particle size, and pore size, have been optimized for high resolution separations.

Compatible with organic solvent used in HPLC and MS under RP conditions

  • Resin is based on a hydrophobic supermacroporous 4µm polymer particles
  • Stable at extreme pH (0 to 14) and high temperature (up to 110 °C)
Efficient with low carry over
  • 1,500Å large pore size polymeric resin
  • Efficient separation of protein molecules with very low carry over
Designed for reversed-phase biomolecule LC and LC/MS separations
  • Superior resolution power for monoclonal antibodies and related substances
  • High efficiency with low carry-over
  • Excellent MS compatibility
  • Wide operating pH range: 0 to 14
  • High temperature stability: up to 110°C
  • High throughput