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LYN B Recombinant Human Protein DFS Item

LYN B Recombinant Human Protein

Manufacturer:  Life Technologies LSP2907

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Catalog No. P2907



Description

Description

LYN is a SRC family kinase expressed predominantly in hematopoietic cells. Activation of LYN has been shown to lead to imatinib resistance in CML patients. LYNB and the slightly shorter LYNA are the two isoforms of LYN.
Specifications

Specifications

AAH59394
Pharma and biopharma, protein assays and analysis, target and lead identification and validation
57.4kDa
80% by SDS-PAGE
–80°C
1 Each
LYN B
LYNB was pre-diluted in enzyme dilution buffer and assayed in 50mM HEPES (pH 7.5), 10mM MgCl2, 2.5mM DTT, 0.01% Triton™ X-100, 10% glycerol and 200μM ATP, 200μg/mL poly [Glu, Tyr] 4:1 substrate and trace [32P]-γ-ATP for 10 minutes at 30°C
Kinase and inhibitors
SRC
950nmoles of phosphate transferred to poly [Glu, Tyr] 4:1 substrate per minute per mg of total protein at 30°C. Activity determined at a final protein concentration of 2μg/mL
His Tag
0.21mg/mL
4067
LYN B Recombinant Human Protein
10μg
For research use only. Not for use in diagnostic procedures
Cytoplasmic tyrosine kinase
LYN B Recombinant Human Protein
Kinase assay
Baculovirus
LYN B Recombinant Human Protein
Human
Documents

For Research Use Only. Not for use in diagnostic procedures.