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Ly-6G (Gr-1) Rat anti-Mouse, Clone: 1A8-Ly6g, Functional Grade, eBioscience™

Rat Monoclonal Antibody, Functional Grade

$230.55 - $433.55

Specifications

Antigen Ly-6G (Gr-1)
Clone 1A8-Ly6g
Host Species Rat
Species Reactivity Mouse
Applications Flow Cytometry
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

501123009

 
affymetrix
16966882
100μg Each for $230.55

501123010

 
affymetrix
16966885
500μg Each for $433.55
Description & Specifications

Specifications

Antigen Ly-6G (Gr-1)
Clone 1A8-Ly6g
Host Species Rat
Species Reactivity Mouse
Applications Flow Cytometry
Applications Functional Assay
Regulatory Status RUO
Conjugate Unlabeled
Format Purified
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, no sodium azide
Concentration 1mg/mL

The monoclonal antibody 1A8-Ly6g reacts with mouse Ly-6G, which is also known as Gr-1. Ly-6G is a 25kDa GPI protein expressed exclusively by neutrophils. Studies suggest an important role in neutrophil infiltration, recruitment and migration. Ly-6G associates with B2 integrins CD11a and CD11b and can attenuate B2 integrin expression and function. The ligand for Ly-6G is currently unknown.

Unlike the RB6-8C5 antibody, 1A8-Ly6g is reported to only bind to Ly-6G found on neutrophils. Moreover, 1A8-Ly6g has been used to deplete neutrophils and reported to have antagonist activity.