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Ly-49H Mouse anti-Mouse, Biotin, Clone: 3D10, eBioscience™

Mouse Monoclonal Antibody

$114.55 - $201.55

Specifications

Antigen Ly-49H
Clone 3D10
Host Species Murine
Species Reactivity Mouse
Applications Flow Cytometry
View More Specs

Disclaimers:

For Research Use Only.



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Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
5011992 Life Technologies
LS13588681
50μg Each for $114.55
5011993 Life Technologies
LS13588682
100μg Each for $201.55
Specifications

Description

The monoclonal antibody 3D10 recognizes Ly-49H, a member of the C-type lectin Ly-49 multigene family of receptors found on natural killer cells. Ly-49H, like Ly-49D, lacks the characteristic ITIM (immunoreceptor tyrosine-based inhibitory motif) and contains an arginine in the transmembrane domain implying these molecules act as activation receptors. Ly-49H is expressed in a subset of NK cells but not NKT (NK1.1CD3+) cells. Natural killer cells can express several Ly-49 proteins. It has been shown that there is preferential staining of Ly-49H with Ly-49D (cat 12-5783). Expression has been confirmed on C57BL/6 and NWNA but not Balb/c or DBA/2 mice. Other mice strains have not been tested. No crossreactivity to Ly-49A, C, D or G2 has been observed. Addition of monoclonal antibody 3D10 to cell cultures induces lysis of target cells.
Description & Specifications

Specifications

Ly-49H
Murine
Flow Cytometry
Biotin
Store at 2-8°C. Do not freeze.
Monoclonal
0.5mg/mL
3D10
Mouse
RUO
Conjugated
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer