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LRRK2 Recombinant Human Protein DFS Item

LRRK2 Recombinant Human Protein

Manufacturer:  Life Technologies LSPV4873

Catalog No. PV4873



Description

Description

LRRK2 is a multidomain protein that includes a kinase domain, a GTPase domain, and a leucine-rich repeat (LRR) domain. Mutations in this gene have been associated with Parkinson's disease.

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  • Specifications

    Specifications

    NP_940980.2
    Pharma and biopharma, protein assays and analysis, target and lead identification and validation
    Liquid
    204.9kDa
    80% by SDS-PAGE
    –80°C
    1 Each
    LRRK2
    LRRK2 was pre-diluted in enzyme dilution buffer and assayed in 20mM Tris (pH 7.5), 10mM MgCl2, 1mM EGTA, 1mM Na3VO4, 5mM β- glycerophosphate, 2mM DTT, 0.02% Polysorbate 20, 100μM ATP, 250μM ERM (LRRKtide) peptide substrate (RLGRDKYKTLRQIRQ) (PV5093) and trace [32P]-γ-ATP for 10 minutes at 30°C
    Kinases and inhibitors
    LRRK Kinase family
    LRRK2 Recombinant Human Protein
    Human
    0.35mg/mL
    Liquid
    120892
    LRRK2 Recombinant Human Protein
    10μg
    For research use only. Not for use in diagnostic procedures
    Serine/threonine kinase
    LRRK2 Recombinant Human Protein
    Kinase assay
    Baculovirus
    aa 970 to 2527
    95nmoles of phosphate transferred to ERM (LRRKtide) peptide substrate (RLGRDKYKTLRQIRQ) (PV5093) per minute per mg of total protein at 30°C. Activity determined at a final protein concentration of 2.08μg/mL
    GST Tag
    Documents

    For Research Use Only. Not for use in diagnostic procedures.