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LRRK2 [G2019S] Recombinant Human Protein, Invitrogen™ DFS Item

LRRK2 is a multidomain protein that includes a kinase domain, a GTPase domain, and a leucine-rich repeat (LRR) domain.

Manufacturer:  Life Technologies LSPV4881

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Catalog No. PV4881



Description

Description

Mutations in the LRRK2 gene have been associated with Parkinson's disease. The G2019S mutation of LRRK2 is associated with an increase in catalytic activity.

Specifications

Specifications

NP_940980.2, G2019S
50mM Tris pH 7.5, 150mM NaCl, 0.5mM EDTA, 0.02% Polysorbate 20, 2mM DTT, 50% glycerol
204.9kDa
Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.
Catalytic, Recombinant
LRRK2 G2019S
Kinase Assay
Baculovirus
aa 970-2527; G2019S
Yes
Target & Lead Identification & Validation|Kinase Biology|Kinase Proteins & Expression Reagents|Protein Biology|Enzyme & Protein Activity Assays|Kinase Activity|Protein Assays and Analysis|Industrial & Applied Science|Pharma & Biopharma
120892
10μg
RUO - research use only
Serine/Threonine Kinases
Leucine-rich repeat kinase 2
Kinases & Inhibitors
LRRK Kinase Family
Human
GST Tag
Documents