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Thermo Scientific™ Lab Vision™ LRP/MVP (Major Vault Protein) Ab-2, Mouse Monoclonal Antibody

Recommended for a variety of techniques, Thermo Scientific™ LRP/MVP (Major Vault Protein) Ab-2, Mouse Monoclonal Antibody provides accurate, reproducible results.

$271.49 - $1,700.29

Specifications

Antigen LRP/MVP (Major Vault Protein) Ab-2
Clone 1032
Applications Immunohistochemistry (Paraffin),Immunoprecipitation,Western Blotting,Immunohistochemistry (Paraffin),Immunoprecipitation,Western Blotting,Immunohistochemistry (Paraffin),Immunoprecipitation,Western Blotting
Classification Monoclonal
Cross Reactivity Human,Rat,Human,Rat
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Products ${productFamilyLength}
Catalog Number Mfr. No. Formulation Quantity Price Quantity  
Catalog Number Mfr. No. Formulation Quantity Price Quantity  
MS664B Thermo Scientific™ Lab Vision™
MS664B
Biotinylated Ab with BSA and Azide 1mL Each for $1,700.29
MS664B0 Thermo Scientific™ Lab Vision™
MS664B0
Biotinylated Ab with BSA and Azide 100μL Each for $367.82
MS664B1 Thermo Scientific™ Lab Vision™
MS664B1
Biotinylated Ab with BSA and Azide 500μL Each for $1,105.61
MS664P Thermo Scientific™ Lab Vision™
MS664P
Purified Ab with BSA and Azide 1mL Each for $1,412.27
MS664P0 Thermo Scientific™ Lab Vision™
MS664P0
Purified Ab with BSA and Azide 100μL Each for $271.49
MS664P1 Thermo Scientific™ Lab Vision™
MS664P1
Purified Ab with BSA and Azide 500μL Each for $862.76
MS664P1ABX Thermo Scientific™ Lab Vision™
MS664P1ABX
Ab without BSA/Azide (Frozen) 100μL Each for $965.41
MS664PABX Thermo Scientific™ Lab Vision™
MS664PABX
Ab without BSA/Azide (Frozen) 200μL Each for $1,464.06
MS664R7 Thermo Scientific™ Lab Vision™
MS664R7
Ready-to-use for IHC (UVLP) 7mL Each for $825.88
Specifications

Description

Recommended for a variety of techniques, Thermo Scientific™ LRP/MVP (Major Vault Protein) Ab-2, Mouse Monoclonal Antibody provides accurate, reproducible results.

Major vault protein (MVP) is identical to lung-resistance related protein (LRP). Its shape is reminiscent of the nucleopore central plug. Treatment of cells with estradiol increases the amount of MVP in nuclear extract. The hormone-dependent interaction of vaults with ER is prevented in vitro by sodium molybdate. Antibodies to progesterone and glucocorticoid receptors are also able to co-immunoprecipitate the MVP. Reportedly, the lung-resistance related protein (LRP) is identical to human MVP. LRP is overexpressed in many neoplastic tissues and cell lines indicating a poor response to chemotherapy.

Host Species: Mouse

Clone: 1032

Isotype: IgG1/κ

Species Reactivity: Human and Rat. Others not known.

Epitope: Not determined

Immunogen: Proteins precipitated with AER317 from the phosphocellulose column flow through of extract of human breast cancer MCF-7 cells

Molecular Weight: 104-110kDa

Positive Control: SKBR-3 cells, Breast tumors

Cellular Localization: Cytoplasmic

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunoprecipitation (Native verified)
  • Gel Supershift
  • Flow Cytometry

Note:

USA: RUO; Int'l: RUO

Description & Specifications

Specifications

LRP/MVP (Major Vault Protein) Ab-2
Immunohistochemistry (Paraffin),Immunoprecipitation,Western Blotting,Immunohistochemistry (Paraffin),Immunoprecipitation,Western Blotting,Immunohistochemistry (Paraffin),Immunoprecipitation,Western Blotting
Human,Rat,Human,Rat
RUO
Primary
IgG2a kappa
1032
Monoclonal
Murine
Cancer and Tumor Biology
Proteins precipitated with AER317 from the phosphocellulose column flow through of extract of human breast cancer MCF-7 cells