missing translation for 'onlineSavingsMsg'
Learn More
Please login to your online account to display your discounted pricing

Thermo Scientific™ Lab Vision™ LRP/MVP (Major Vault Protein) Ab-2, Mouse Monoclonal Antibody

Recommended for a variety of techniques, Thermo Scientific™ LRP/MVP (Major Vault Protein) Ab-2, Mouse Monoclonal Antibody provides accurate, reproducible results.

$263.84 - $1,652.39

Specifications

Antigen LRP/MVP (Major Vault Protein) Ab-2
Clone 1032
Applications Immunohistochemistry (Paraffin),Immunoprecipitation,Western Blotting,Immunohistochemistry (Paraffin),Immunoprecipitation,Western Blotting,Immunohistochemistry (Paraffin),Immunoprecipitation,Western Blotting
Classification Monoclonal
Host Species Murine
View More Specs


Products ${productFamilyLength}
Catalog Number Mfr. No. Formulation Quantity Price Quantity  
Catalog Number Mfr. No. Formulation Quantity Price Quantity  
MS664B Thermo Scientific™ Lab Vision™
MS664B
Biotinylated Ab with BSA and Azide 1mL Each for $1,652.39
MS664B0 Thermo Scientific™ Lab Vision™
MS664B0
Biotinylated Ab with BSA and Azide 100μL Each for $357.47
MS664B1 Thermo Scientific™ Lab Vision™
MS664B1
Biotinylated Ab with BSA and Azide 500μL Each for $1,074.47
MS664P Thermo Scientific™ Lab Vision™
MS664P
Purified Ab with BSA and Azide 1mL Each for $1,372.47
MS664P0 Thermo Scientific™ Lab Vision™
MS664P0
Purified Ab with BSA and Azide 100μL Each for $263.84
MS664P1 Thermo Scientific™ Lab Vision™
MS664P1
Purified Ab with BSA and Azide 500μL Each for $838.47
MS664P1ABX Thermo Scientific™ Lab Vision™
MS664P1ABX
Ab without BSA/Azide (Frozen) 100μL Each for $938.22
MS664PABX Thermo Scientific™ Lab Vision™
MS664PABX
Ab without BSA/Azide (Frozen) 200μL Each for $1,422.82
MS664R7 Thermo Scientific™ Lab Vision™
MS664R7
Ready-to-use for IHC (UVLP) 7mL Each for $802.61
Specifications

Description

Recommended for a variety of techniques, Thermo Scientific™ LRP/MVP (Major Vault Protein) Ab-2, Mouse Monoclonal Antibody provides accurate, reproducible results.

Major vault protein (MVP) is identical to lung-resistance related protein (LRP). Its shape is reminiscent of the nucleopore central plug. Treatment of cells with estradiol increases the amount of MVP in nuclear extract. The hormone-dependent interaction of vaults with ER is prevented in vitro by sodium molybdate. Antibodies to progesterone and glucocorticoid receptors are also able to co-immunoprecipitate the MVP. Reportedly, the lung-resistance related protein (LRP) is identical to human MVP. LRP is overexpressed in many neoplastic tissues and cell lines indicating a poor response to chemotherapy.

Host Species: Mouse

Clone: 1032

Isotype: IgG1/κ

Species Reactivity: Human and Rat. Others not known.

Epitope: Not determined

Immunogen: Proteins precipitated with AER317 from the phosphocellulose column flow through of extract of human breast cancer MCF-7 cells

Molecular Weight: 104-110kDa

Positive Control: SKBR-3 cells, Breast tumors

Cellular Localization: Cytoplasmic

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunoprecipitation (Native verified)
  • Gel Supershift
  • Flow Cytometry

Note:

USA: RUO; Int'l: RUO

Description & Specifications

Specifications

LRP/MVP (Major Vault Protein) Ab-2
Immunohistochemistry (Paraffin),Immunoprecipitation,Western Blotting,Immunohistochemistry (Paraffin),Immunoprecipitation,Western Blotting,Immunohistochemistry (Paraffin),Immunoprecipitation,Western Blotting
Murine
Cancer and Tumor Biology
Proteins precipitated with AER317 from the phosphocellulose column flow through of extract of human breast cancer MCF-7 cells
1032
Monoclonal
RUO
Primary
IgG2a kappa