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LMO2 Mouse anti-Human, Clone: 1A9-3B11, eBioscience™

Mouse Monoclonal Antibody

$172.55 - $433.55

Specifications

Antigen LMO2
Clone 1A9-3B11
Host Species Mouse
Species Reactivity Human
Applications Immunohistochemistry
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5013840

 
life technologies
LS14989980
25μg Each for $172.55

5013841

 
life technologies
LS14989982
100μg Each for $433.55
Description & Specifications

Specifications

Antigen LMO2
Clone 1A9-3B11
Host Species Mouse
Species Reactivity Human
Applications Immunohistochemistry
Regulatory Status RUO
Conjugate Unlabeled
Format Purified
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.5mg/mL

This 1A9-3B11 monoclonal antibody reacts with human LMO2, a member of the LIM-only family of zinc finger proteins. LMO2 possesses two LIM domains for homodimerization and an N-terminal transactivation domain. This 24kDa transcription factor can be found as part of a transcriptional complex composed of TAL1, E47, GATA-1, and LDB1 proteins. LMO2 is expressed in myeloid cells, germinal center B cells, vascular endothelium, and a variety of cancers, including diffuse large B cell lymphomas (DLBCL), T cell acute lymphoblastic lymphomas, and vascular neoplasms. Expression of LMO2 in germinal center B cells has been shown to be regulated by microRNAs, specifically hsa-miR-223. Although the function of LMO2 remains unclear in germinal center B cells, this factor is involved in hematopoiesis and oncogenesis. In addition, expression of this molecule has been demonstrated to be prognostic marker for survival in DLBCL patients.