Please login to your online account to display your discounted pricing

LMO2 Mouse anti-Human, Clone: 1A9-3B11, eBioscience™

Mouse Monoclonal Antibody

$172.55 - $433.55

Specifications

Antigen LMO2
Clone 1A9-3B11
Host Species Mouse
Species Reactivity Human
Applications Immunohistochemistry
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5013840

 
affymetrix
14-9899-80
25μg Each for $172.55

5013841

 
affymetrix
14-9899-82
100μg Each for $433.55
Description & Specifications

Specifications

Antigen LMO2
Clone 1A9-3B11
Host Species Mouse
Species Reactivity Human
Applications Immunohistochemistry
Regulatory Status RUO
Conjugate Unlabeled
Format Purified
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.5mg/mL

This 1A9-3B11 monoclonal antibody reacts with human LMO2, a member of the LIM-only family of zinc finger proteins. LMO2 possesses two LIM domains for homodimerization and an N-terminal transactivation domain. This 24kDa transcription factor can be found as part of a transcriptional complex composed of TAL1, E47, GATA-1, and LDB1 proteins. LMO2 is expressed in myeloid cells, germinal center B cells, vascular endothelium, and a variety of cancers, including diffuse large B cell lymphomas (DLBCL), T cell acute lymphoblastic lymphomas, and vascular neoplasms. Expression of LMO2 in germinal center B cells has been shown to be regulated by microRNAs, specifically hsa-miR-223. Although the function of LMO2 remains unclear in germinal center B cells, this factor is involved in hematopoiesis and oncogenesis. In addition, expression of this molecule has been demonstrated to be prognostic marker for survival in DLBCL patients.