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LMO2 Mouse anti-Human, Clone: 1A9-3B11, eBioscience™

Mouse Monoclonal Antibody

$172.55 - $394.68

Specifications

Antigen LMO2
Clone 1A9-3B11
Host Species Murine
Applications Immunohistochemistry
Regulatory Status RUO
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
5013840 Life Technologies
LS14989980
25μg Each for $172.55
5013841 Life Technologies
LS14989982
100μg Each for $394.68
Specifications

Description

This 1A9-3B11 monoclonal antibody reacts with human LMO2, a member of the LIM-only family of zinc finger proteins. LMO2 possesses two LIM domains for homodimerization and an N-terminal transactivation domain. This 24kDa transcription factor can be found as part of a transcriptional complex composed of TAL1, E47, GATA-1, and LDB1 proteins. LMO2 is expressed in myeloid cells, germinal center B cells, vascular endothelium, and a variety of cancers, including diffuse large B cell lymphomas (DLBCL), T cell acute lymphoblastic lymphomas, and vascular neoplasms. Expression of LMO2 in germinal center B cells has been shown to be regulated by microRNAs, specifically hsa-miR-223. Although the function of LMO2 remains unclear in germinal center B cells, this factor is involved in hematopoiesis and oncogenesis. In addition, expression of this molecule has been demonstrated to be prognostic marker for survival in DLBCL patients.
Description & Specifications

Specifications

LMO2
Murine
RUO
Purified
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
1A9-3B11
Immunohistochemistry
Unlabeled
Store at 2-8°C.
Monoclonal
0.5mg/mL