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Lincomycin hydrochloride, Thermo Scientific Chemicals
Lincomycin hydrochloride, CAS # 859-18-7, is a compound showing antibacterial activity against a wide variety of bacteria, including Staphylococcal, Streptococcal, and Bacteroides fragilis infections. It also shows inhibitory activity against protein synthesis.
Supplier: Thermo Scientific Chemicals J6125103
Description
Lincomycin hydrochloride is used to study the inhibition of protein synthesis, bacterial antibiotic resistance and protein and surfactant binding. It has been used in the treatment of Staphylococcal, Streptococcal, and Bacterioides fragilis infections.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Description
Lincomycin hydrochloride is a lincosamide compound with antibacterial activity originally identified in the actinomycete, Streptomyces lincolnensis, with activity against gram-positive cocci and anaerobic bacteria
Lincomycin inhibits bacterial protein synthesis by forming cross-links within the peptidyl transferase loop region of the 23S rRNA
Application
Lincomycin hydrochloride is commonly used to study the inhibition of protein synthesis, bacterial antibiotic resistance, and protein and surfactant binding
It has been used against Staphylococcal, Streptococcal, and Bacteroides fragilis species
It is protective against the development of mastitis in a mouse model of acute mastitis induced by S. aureus
Specifications
| Lincomycin Hydrochloride | |
| Crystalline Powder | |
| C18H35ClN2O6S | |
| 4171650 | |
| POUMFISTNHIPTI-OXVORJCQSA-N | |
| (2R,4R)-N-[(1R,2R)-2-hydroxy-1-[(2S,3R,4S,5R,6S)-3,4,5-trihydroxy-6-methylsulfanyloxan-2-yl]propyl]-1-methyl-4-propylpyrrolidine-2-carboxamide;hydrochloride | |
| 124080936 | |
| White |
| Lincomycin hydrochloride | |
| 859-18-7 | |
| MFCD00058237 | |
| Soluble in water | |
| CCCC1CC(N(C1)C)C(=O)NC(C2C(C(C(C(O2)SC)O)O)O)C(C)O.Cl | |
| 442.996 | |
| 443 | |
| 1 g |
Chemical Identifiers
| 859-18-7 | |
| 442.996 | |
| POUMFISTNHIPTI-OXVORJCQSA-N | |
| (2R,4R)-N-[(1R,2R)-2-hydroxy-1-[(2S,3R,4S,5R,6S)-3,4,5-trihydroxy-6-methylsulfanyloxan-2-yl]propyl]-1-methyl-4-propylpyrrolidine-2-carboxamide;hydrochloride |
| C18H35ClN2O6S | |
| MFCD00058237 | |
| 124080936 | |
| CCCC1CC(N(C1)C)C(=O)NC(C2C(C(C(C(O2)SC)O)O)O)C(C)O.Cl |
Safety and Handling
GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
H315-H319-H335
EINECSNumber : 212-726-7
RTECSNumber : RH6315000
TSCA : No
Recommended Storage : Keep cold
RUO – Research Use Only