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LanthaScreen™ Tb-peIF2a (pSer52) Antibody DFS Item

LanthaScreen™ Tb-peIF2a (pSer52) Antibody

Manufacturer:  Life Technologies LSPV4816

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Catalog No. PV4816

Please call Customer Service at 1-800-234-7437 or send an email to help@thermofisher.com for assistance.


Description

Description

The alpha subunit of Eukaryotic initiation factor 2 (eIF2alpha) plays a key regulatory role in protein synthesis. In response to a cellular stress, phosphorylation of eIF2alpha at Ser52 occurs by the EIF2AK family of kinases including PERK (EIF2AK3) and PKR (EIF2AK2) to prohibit the initiation of protein synthesis.
For use in combination with the GFP-EIF2alpha physiological protein substrate (PV4809) to evaluate inhibitors in medium to high throughput screening applications.
Specifications

Specifications

Serine/threonine kinase
0.47mg/mL
Liquid
1mg
–20°C
Primary
Biochemical Kinase Assays, Drug Discovery and Development, Kinase Biology, Pharma and Biopharma, Target and Lead Identification and Validation
Tb (Terbium), lanthanide chelates
150kDa
RUO, For research use only
Primary
1 Each
Documents

For Research Use Only. Not for use in diagnostic procedures.