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Thermo Scientific™ Lab Vision™ Laminin B2/γ 1 Ab-1, Rat Monoclonal Antibody


Recommended for Immunohistochemistry (Acetone-fixed frozen and acid-alcohol-fixed, paraffin-embedded), Immunofluorescence and Immunoprecipitation (Native and denatured), Thermo Scientific™ Laminin B2/γ1 Ab-1, Rat Monoclonal Antibody provides accurate, reproducible results.

Manufacturer: thermo scientific™ lab vision™  RT795P1ABX

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Catalog No. RT795P1ABX

  • / Each
 

Description & Specifications

Specifications

Antigen Laminin B2/gamma1 Ab-1
Applications Immunohistochemistry (Frozen)
Applications Immunoprecipitation
Classification Monoclonal
Clone A5
Concentration 1mg/mL
Conjugate Unlabeled
Cross Reactivity Human
Format Concentrated
Host Species Rat
Immunogen Murine EHS laminin preparation
Isotype IgG2a kappa
Quantity 100µL
Regulatory Status RUO
Research Discipline Extracellular Matrix
Type Primary

Recommended for Immunohistochemistry (Acetone-fixed frozen and acid-alcohol-fixed, paraffin-embedded), Immunofluorescence and Immunoprecipitation (Native and denatured), Thermo Scientific™ Laminin B2/γ1 Ab-1, Rat Monoclonal Antibody provides accurate, reproducible results.

Laminins are large heterotrimeric, noncollagenous glycoproteins composed of α, β, and γ chains. They are ubiquitously present in basement membrane (BM) along with entactin/nidogen (EN), collagen type IV (CIV), and large heparan sulfate proteoglycan (HSPG), which interact specifically with each other to form a continuous and regular BM. Alterations of BM integrity, from local discontinuities up to complete loss, are described in many types of human and animal epithelial neoplasms.

Host Species: Rat

Clone: A5

Isotype: IgG2a/κ

Species Reactivity: Human and Mouse. Others not known.

Epitope: Not determined

Immunogen: Murine EHS laminin preparation

Molecular Weight: ∽210kDa

Positive Control: LS174T cells, Normal colon or colon CA

Cellular Localization: Basement membrane Specificity of Ab-1 was established by immunoprecipitation and immunofluorescence of human skeletal muscle and kidney with laminin chain-specific MAbs. Ab-1 stains uniformly all human and murine basement membranes.

Recommended for:

  • Immunohistochemistry (Acetone-fixed frozen and acid-alcohol-fixed, paraffin-embedded)
  • Immunofluorescence
  • Immunoprecipitation (Native and denatured)

Note:

USA: RUO; Int'l: RUO