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Lamin A/C Mouse, Clone: 4A7, eBioscience™

Mouse Monoclonal Antibody

$133.32 - $133.32

Specifications

Antigen Lamin A/C
Clone 4A7
Host Species Murine
Gene Alias LMNA, LMNC
Species Reactivity Hamster, Human, Mouse, Rabbit
View More Specs

Disclaimers:

For Research Use Only.



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Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
501122797 Life Technologies
LS14968880
25μg Each for $133.32
Specifications

Description

The monoclonal antibody 4A7 recognizes human, mouse, rabbit and hamster lamin A/C. Lamins are nuclear intermediate filament proteins that provide framework for the nuclear envelope, maintain cell morphology, and protect the nucleus from mechanical, thermal, and oxidative stresses. Lamins also play a role in nuclear assembly, chromatin organization, DNA replication, RNA transcription, cell signaling, and apoptosis. Lamin C is a splice variant of Lamin A and both are A-type lamins. Lamin A and C are crucial for skeletal and cardiac development and function. Defects in A-type lamins result in cardiomyopathy, muscular dystrophy, peripheral neuropathy, lipodystrophy, restrictive dermopathy, and progeroid disorders.
Description & Specifications

Specifications

Lamin A/C
Murine
Hamster, Human, Mouse, Rabbit
RUO
Purified
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
4A7
LMNA, LMNC
ELISA,Immunocytochemistry,Immunohistochemistry (Frozen),Microscopy,Western Blot
Unlabeled
Store at 2-8°C.
Monoclonal
0.5mg/mL