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Lamin A/C Mouse, Alexa Fluor 488, Clone: 4A7, eBioscience™

Mouse Monoclonal Antibody

$175.45 - $442.25

Specifications

Antigen Lamin A/C
Clone 4A7
Host Species Murine
Gene Alias LMNA, LMNC
Applications Immunocytochemistry,Immunohistochemistry (Frozen),Microscopy
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
501124626 Life Technologies
LS53968880
25μg Each for $175.45
501124627 Life Technologies
LS53968882
100μg Each for $442.25
Specifications

Description

The monoclonal antibody 4A7 recognizes human, mouse, rabbit and hamster lamin A/C. Lamins are nuclear intermediate filament proteins that provide framework for the nuclear envelope, maintain cell morphology, and protect the nucleus from mechanical, thermal, and oxidative stresses. Lamins also play a role in nuclear assembly, chromatin organization, DNA replication, RNA transcription, cell signaling, and apoptosis. Lamin C is a splice variant of Lamin A and both are A-type lamins. Lamin A and C are crucial for skeletal and cardiac development and function. Defects in A-type lamins result in cardiomyopathy, muscular dystrophy, peripheral neuropathy, lipodystrophy, restrictive dermopathy, and progeroid disorders.
Description & Specifications

Specifications

Lamin A/C
Murine
Immunocytochemistry,Immunohistochemistry (Frozen),Microscopy
Alexa Fluor 488
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
0.5mg/mL
4A7
LMNA, LMNC
RUO
Conjugated
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer