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Thermo Scientific™ Lab Vision™ Ku (p80) Ab-2, Mouse Monoclonal Antibody


Ensure accurate, reproducible results in a variety of molecular biology techniques with the Thermo Scientific™ Ku (p80) Ab-2, Mouse Monoclonal Antibody..

Manufacturer: thermo scientific™ lab vision™  MS285P1ABX

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Catalog No. MS285P1ABX

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Description & Specifications

Specifications

Antigen Ku (p80) Ab-2
Applications Flow Cytometry
Applications Immunofluorescence
Applications Immunoprecipitation
Applications Western Blotting
Classification Monoclonal
Clone 111
Concentration 1mg/mL
Conjugate Unlabeled
Cross Reactivity Human
Cross Reactivity Non-Human Primate
Format Concentrated
Formulation Ab without BSA/Azide (Frozen)
Host Species Mouse
Immunogen Human B cell nuclei from plasmacytoid 2p68 cells
Isotype IgG2a kappa
Quantity 100µL
Regulatory Status RUO
Research Discipline DNA Repair
Type Primary

Ensure accurate, reproducible results in a variety of molecular biology techniques with the Thermo Scientific™ Ku (p80) Ab-2, Mouse Monoclonal Antibody.

The Ku autoantigen is a heterodimer of 70kDa (p70) and ∽80kDa (p80) proteins. The p70/p80 dimer is important for function of a 460kDa DNA-dependent protein kinase that phosphorylates certain transcription factors, including Sp1, Oct-1, p53, and SV40 large T antigen in vitro. Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis.

Host Species: Mouse

Clone: 111

Isotype: IgG1/κ

Species Reactivity: Human and Monkey. Does not react with cow, rabbit, mouse and rat.

Epitope: aa 610-705

Immunogen: Human B-cell nuclei from plasmacytoid 2p68 cells

Molecular Weight: 80kDa

Positive Control: HeLa, T47D or BT474 cells

Cellular Localization: Nuclear

Recommended for:

  • Western Blotting
  • Immunofluorescence
  • Immunoprecipitation (Native and denatured)
  • Flow Cytometry

Note:

USA: RUO; Int'l: RUO