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Thermo Scientific™ Lab Vision™ Ku (p70/p80) Ab-3, Mouse Monoclonal Antibody

Recommended for multiple molecular biology techniques, Thermo Scientific™ Ku (p70/p80) Ab-3, Mouse Monoclonal Antibody provides accurate, reproducible results.

$277.39 - $1,209.24

Specifications

Antigen Ku (p70/p80) Ab-3
Clone 162
Applications Flow Cytometry,Immunofluorescence,Immunohistochemistry (Paraffin),Flow Cytometry,Immunofluorescence,Immunohistochemistry (Paraffin),Flow Cytometry,Immunofluorescence,Immunohistochemistry (Paraffin)
Classification Monoclonal
Conjugate Unlabeled
View More Specs


Products ${productFamilyLength}
Catalog Number Mfr. No. Formulation Quantity Price Quantity  
Catalog Number Mfr. No. Formulation Quantity Price Quantity  
MS286P Thermo Scientific™ Lab Vision™
MS286P
Purified Ab with BSA and Azide 1mL Each for $1,122.71
MS286P0 Thermo Scientific™ Lab Vision™
MS286P0
Purified Ab with BSA and Azide 100μL Each for $277.39
MS286P1 Thermo Scientific™ Lab Vision™
MS286P1
Purified Ab with BSA and Azide 500μL Each for $712.31
MS286P1ABX Thermo Scientific™ Lab Vision™
MS286P1ABX
Ab without BSA/Azide (Frozen) 100μL Each for $799.06
MS286PABX Thermo Scientific™ Lab Vision™
MS286PABX
Ab without BSA/Azide (Frozen) 200μL Each for $1,209.24
MS286R7 Thermo Scientific™ Lab Vision™
MS286R7
Ready-to-use for IHC (UVLP) 7mL Each for $834.22
Specifications

Description

Recommended for multiple molecular biology techniques, Thermo Scientific™ Ku (p70/p80) Ab-3, Mouse Monoclonal Antibody provides accurate, reproducible results.

The Ku autoantigen is a heterodimer of 70kDa (p70) and ∽80kDa (p80) proteins. The p70/p80 dimer is important for function of a 460kDa DNA-dependent protein kinase that phosphorylates certain transcription factors, including Sp1, Oct-1, p53, and SV40 large T antigen in vitro. Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis.

Host Species: Mouse

Clone: 162

Isotype: IgG2a

Species Reactivity: Human, Monkey, Xenopus. Mouse and Rat (Immunoprecipitation only). Does not react with cow and rabbit.

Epitope: A conformational epitope of p70/p80 dimer, which is destroyed during Western Blotting

Immunogen: Human B-cell nuclei from plasmacytoid 2p68 cells

Molecular Weight: 70kDa and 80kDa

Positive Control: Tonsil

Cellular Localization: Nuclear

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting (Not suitable)
  • Immunofluorescence
  • Affinity Purification
  • Flow Cytometry
  • Gel Supershift

General References:

1. Wang J, et. al. Molecular Biology Reports, 1993, 18(1):15-28.

2. Reeves WH, et. al. Journal of Experimental Medicine, 1985, 161(1):18-39.

Description & Specifications

Specifications

Ku (p70/p80) Ab-3
Flow Cytometry,Immunofluorescence,Immunohistochemistry (Paraffin),Flow Cytometry,Immunofluorescence,Immunohistochemistry (Paraffin),Flow Cytometry,Immunofluorescence,Immunohistochemistry (Paraffin)
Unlabeled
Murine
DNA Repair
Human B cell nuclei from plasmacytoid 2p68 cells
162
Monoclonal
Human,Non-Human Primate,Xenopus,Human,Non-Human Primate,Xenopus,Human,Non-Human Primate,Xenopus
RUO
Primary
IgG2a