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Thermo Scientific™ Lab Vision™ Ku (p70/p80) Ab-3, Mouse Monoclonal Antibody

Recommended for multiple molecular biology techniques, Thermo Scientific™ Ku (p70/p80) Ab-3, Mouse Monoclonal Antibody provides accurate, reproducible results.

$257.88 - $1,124.63

Specifications

Antigen Ku (p70/p80) Ab-3
Clone 162
Applications Flow Cytometry
Applications Immunofluorescence
Applications Immunohistochemistry (Paraffin)
View More Specs
Products
Catalog Number Mfr. No. Formulation Quantity Price Quantity    

MS286P

 
thermo scientific™ lab vision™
MS-286-P
Purified Ab with BSA and Azide 1mL Each for $1,044.24

MS286P0

 
thermo scientific™ lab vision™
MS-286-P0
Purified Ab with BSA and Azide 100µL Each for $257.88

MS286P1

 
thermo scientific™ lab vision™
MS-286-P1
Purified Ab with BSA and Azide 500µL Each for $662.51

MS286P1ABX

 
thermo scientific™ lab vision™
MS286P1ABX
Ab without BSA/Azide (Frozen) 100µL Each for $743.12

MS286PABX

 
thermo scientific™ lab vision™
MS-286-PABX
Ab without BSA/Azide (Frozen) 200µL Each for $1,124.63

MS286R7

 
thermo scientific™ lab vision™
MS-286-R7
Ready-to-use for IHC (UVLP) 7mL Each for $775.86
Description & Specifications

Specifications

Antigen Ku (p70/p80) Ab-3
Clone 162
Applications Flow Cytometry
Applications Immunofluorescence
Applications Immunohistochemistry (Paraffin)
Applications Flow Cytometry
Applications Immunofluorescence
Applications Immunohistochemistry (Paraffin)
Applications Flow Cytometry
Applications Immunofluorescence
Applications Immunohistochemistry (Paraffin)
Classification Monoclonal
Conjugate Unlabeled
Cross Reactivity Human
Cross Reactivity Non-Human Primate
Cross Reactivity Xenopus
Cross Reactivity Human
Cross Reactivity Non-Human Primate
Cross Reactivity Xenopus
Cross Reactivity Human
Cross Reactivity Non-Human Primate
Cross Reactivity Xenopus
Host Species Mouse
Regulatory Status RUO
Research Discipline DNA Repair
Type Primary
Immunogen Human B cell nuclei from plasmacytoid 2p68 cells
Isotype IgG2a

Recommended for multiple molecular biology techniques, Thermo Scientific™ Ku (p70/p80) Ab-3, Mouse Monoclonal Antibody provides accurate, reproducible results.

The Ku autoantigen is a heterodimer of 70kDa (p70) and ∽80kDa (p80) proteins. The p70/p80 dimer is important for function of a 460kDa DNA-dependent protein kinase that phosphorylates certain transcription factors, including Sp1, Oct-1, p53, and SV40 large T antigen in vitro. Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis.

Host Species: Mouse

Clone: 162

Isotype: IgG2a

Species Reactivity: Human, Monkey, Xenopus. Mouse and Rat (Immunoprecipitation only). Does not react with cow and rabbit.

Epitope: A conformational epitope of p70/p80 dimer, which is destroyed during Western Blotting

Immunogen: Human B-cell nuclei from plasmacytoid 2p68 cells

Molecular Weight: 70kDa and 80kDa

Positive Control: Tonsil

Cellular Localization: Nuclear

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting (Not suitable)
  • Immunofluorescence
  • Affinity Purification
  • Flow Cytometry
  • Gel Supershift

General References:

1. Wang J, et. al. Molecular Biology Reports, 1993, 18(1):15-28.

2. Reeves WH, et. al. Journal of Experimental Medicine, 1985, 161(1):18-39.