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Thermo Scientific™ Lab Vision™ Ku (p70/p80) Ab-3, Mouse Monoclonal Antibody

Recommended for multiple molecular biology techniques, Thermo Scientific™ Ku (p70/p80) Ab-3, Mouse Monoclonal Antibody provides accurate, reproducible results.

Manufacturer:  Thermo Scientific™ Lab Vision™ MS286P1ABX

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Catalog No. MS286P1ABX


 

Specifications

Description

Recommended for multiple molecular biology techniques, Thermo Scientific™ Ku (p70/p80) Ab-3, Mouse Monoclonal Antibody provides accurate, reproducible results.

The Ku autoantigen is a heterodimer of 70kDa (p70) and ∽80kDa (p80) proteins. The p70/p80 dimer is important for function of a 460kDa DNA-dependent protein kinase that phosphorylates certain transcription factors, including Sp1, Oct-1, p53, and SV40 large T antigen in vitro. Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis.

Host Species: Mouse

Clone: 162

Isotype: IgG2a

Species Reactivity: Human, Monkey, Xenopus. Mouse and Rat (Immunoprecipitation only). Does not react with cow and rabbit.

Epitope: A conformational epitope of p70/p80 dimer, which is destroyed during Western Blotting

Immunogen: Human B-cell nuclei from plasmacytoid 2p68 cells

Molecular Weight: 70kDa and 80kDa

Positive Control: Tonsil

Cellular Localization: Nuclear

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting (Not suitable)
  • Immunofluorescence
  • Affinity Purification
  • Flow Cytometry
  • Gel Supershift
Description & Specifications

Specifications

Ku (p70/p80) Ab-3
Monoclonal
1mg/mL
Human,Non-Human Primate,Xenopus
Ab without BSA/Azide (Frozen)
Human B cell nuclei from plasmacytoid 2p68 cells
100μL
DNA Repair
Monoclonal
Flow Cytometry,Immunofluorescence,Immunohistochemistry (Paraffin)
162
Unlabeled
Concentrated
Murine
IgG2a
RUO
Primary
Human,Non-human Primate,Xenopus