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Thermo Scientific™ Lab Vision™ Ku (p70) Ab-4, Mouse Monoclonal Antibody

Recommended for multiple molecular biology techniques, Thermo Scientific™ Ku (p70) Ab-4, Mouse Monoclonal Antibody provides accurate, reproducible results.

Manufacturer:  Thermo Scientific™ Lab Vision™ MS329P1ABX

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Catalog No. MS329P1ABX


 

Specifications

Description

Recommended for multiple molecular biology techniques, Thermo Scientific™ Ku (p70) Ab-4, Mouse Monoclonal Antibody provides accurate, reproducible results. Mouse Monoclonal Antibody

The Ku autoantigen is a heterodimer of 70kDa (p70) and ∽80kDa (p80) proteins. The p70/p80 dimer is important for function of a 460kDa DNA-dependent protein kinase that phosphorylates certain transcription factors, including Sp1, Oct-1, p53, and SV40 large T antigen in vitro. Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis.

Host Species: Mouse

Clone: N3H10

Isotype: IgG2b

Species Reactivity: Human, Monkey and Xenopus. Mouse and Hamster (Western Blotting only). Does not react with cow, rabbit and sea urchin.

Epitope: aa 506-541

Immunogen: Human placental extract designated as PSE1-PL

Molecular Weight: 70kDa

Positive Control: BT474, T47D, HEP-G-2 or HeLa cells; Tonsil

Cellular Localization: Nuclear

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunofluorescence
  • Immunoprecipitation (Native and denatured)

Note:

USA: RUO; Int'l: RUO

Description & Specifications

Specifications

Ku (p70) Ab-4
Monoclonal
1mg/mL
Human,Non-Human Primate,Xenopus
Ab without BSA/Azide (Frozen)
Human placental extract designated as PSE1-PL
100μL
DNA Repair
Monoclonal
Immunofluorescence,Immunohistochemistry (Paraffin),Immunoprecipitation,Western Blotting
N3H10
Unlabeled
Concentrated
Murine
IgG2b
RUO
Primary
Human,Non-human Primate,Xenopus