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KLRG1 Mouse anti-Human, APC, Clone: 13F12F2, eBioscience™

Mouse Monoclonal Antibody

$216.05 - $506.05

Specifications

Antigen KLRG1
Clone 13F12F2
Host Species Mouse
Gene Alias MAFA
Species Reactivity Human
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

501123220

 
affymetrix
17948841
25 tests Each for $216.05

501123221

 
affymetrix
17948842
100 tests Each for $506.05
Description & Specifications

Specifications

Antigen KLRG1
Clone 13F12F2
Host Species Mouse
Gene Alias MAFA
Species Reactivity Human
Applications Flow Cytometry
Regulatory Status RUO
Conjugate APC
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 5μL (0.25μg)/test

This 13F12F2 monoclonal antibody reacts with human killer cell lectin-like receptor subfamily G, member 1 (KLRG1), a type II transmembrane inhibitor receptor of the C-type lectin superfamily that contains an ITIM domain. This inhibitory receptor is expressed on subsets of gamma-delta T cells, NK (CD56dim), CD8+ and CD4+ T Cells. KLRG1 is expressed primarily by cells with an effector/memory phenotype that are short-lived, but capable of immediate effector cell function. Cadherin-E, -N, and -R are ligands for KLRG1. Cadherin/KLRG1 interaction inhibits cytolytic activity and proliferation. The percentage of KLRG1 positive cells can vary considerably, depending on antigen experience.

The clones 13F12F2 and 13A2 appear to recognize a similar epitope based on cross-blocking studies.