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KIT [V654A] Recombinant Human Protein, Invitrogen™ DFS Item

KIT is a proto-oncogene encoding a transmembrane tyrosine kinase receptor for stem cell factor required for normal hematopoiesis, melangenesis and gametogenesis.

Manufacturer:  Life Technologies LSPV4291

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Catalog No. PV4291



Description

Description

Mutations in KIT are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous leukemia, and piebaldism. The clinically observed V654A mutant has been demonstrated to be resistant to inhibition with imatinib.

Specifications

Specifications

NP_000213, V654A
Frozen
53.2kDa
Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.
Cytoplasmic
Kinase Assay
PDGFR Kinase Family
Yes
Protein Biology|Enzyme & Protein Activity Assays|Kinase Activity|Protein Assays and Analysis
50mM Tris (pH 7.5), 150mM NaCl, 0.5mM EDTA, 0.02% Triton X-100, 2mM DTT, 50% Glycerol
1mg
RUO - research use only
KIT V654A
Baculovirus
Human
His Tag
Documents