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Tocris™ K 02288

Type 1 BMP receptor inhibitor

$276.32 - $1,163.11

Specifications

Product Type K 02288
Inhibitors K 02288
Molecular Weight 352.38
Purity >99
View More Specs

 Disclaimers

For Research Use Only

Products
Catalog Number Mfr. No. Quantity Price Quantity    

498610R

 
tocris™
4986/10
10mg Each for $276.32

498650R

 
tocris™
4986/50
50mg Each for $1,163.11
Description & Specifications

Specifications

Product Type K 02288
Inhibitors K 02288
Molecular Weight 352.38
Purity >99

Potent and selective inhibitor of type I bone morphogenic protein (BMP) receptors (IC50 values are 1.1, 1.8, 6.4, 34.4, 220, 302 and 321nM for ALK2, ALK1, ALK6, ALK3, ActRIIA, ALK4 and ALK5 respectively). Reduces BMP4-induced Smad1/5/8 phosphorylation in vitro (IC50 = 100nM) and induces dorsalization of zebrafish embryos.

  • Chemical Name: 3-[(6-Amino-5-(3,4,5-trimethoxyphenyl)-3-pyridinyl]phenol
  • Formula: C20H20N2O4
  • CAS Number: 1431985-92-0
  • Solubility: Soluble to 100mM in DMSO and to 10mM in ethanol with gentle warming
  • Purity: >99