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JAK3 Recombinant Human Protein 
JAK3 Recombinant Human Protein
Manufacturer: Life Technologies LSPV3855
Description
Janus kinase 3 (JAK3) phosphorylates members of the STAT (signal transduction and activators of transcription) family. JAK3 is predominantly expressed in immune cells and transduces a signal in response to activation of interleukin receptors.Specifications
| NP_000206 | |
| Cell viability, proliferation and function, pharma and biopharma, protein assays and analysis, target and lead identification and validation | |
| 67.4kDa | |
| 75% by SDS-PAGE | |
| –80°C | |
| 1 Each | |
| JAK3, LJAK, JAKL | |
| JAK3 was pre-diluted in enzyme dilution buffer and assayed in 50mM Tris (pH 7.5), 10mM MgCl2, 0.25mM EGTA, 0.1mM Na3VO4, 5mM β-glycerophosphate, 2.5mM DTT, 0.01% Triton™ X-100, 200μM ATP, 200μg/mL Abl1 peptide substrate (EAIYAAPFAKKK) and trace [32P]-γ-ATP for 10 minutes at 30°C | |
| Kinase and inhibitors | |
| JAK | |
| JAK3 Recombinant Human Protein | |
| Human |
| 0.37mg/mL | |
| 3718 | |
| JAK3 Recombinant Human Protein | |
| 10μg | |
| For research use only. Not for use in diagnostic procedures | |
| Cytoplasmic tyrosine kinase | |
| JAK3 Recombinant Human Protein | |
| Kinase assay | |
| Baculovirus | |
| Amino acids 781-1124 | |
| 160nmoles of phosphate transferred to Abl1 peptide substrate (EAIYAAPFAKKK) per minute per mg of total protein at 30°C. Activity determined at a final protein concentration of 1.67μg/mL | |
| GST Tag |
For Research Use Only. Not for use in diagnostic procedures.