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JAK3 Recombinant Human Protein DFS Item

JAK3 Recombinant Human Protein

Manufacturer:  Life Technologies LSPV3855

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Catalog No. PV3855



Description

Description

Janus kinase 3 (JAK3) phosphorylates members of the STAT (signal transduction and activators of transcription) family. JAK3 is predominantly expressed in immune cells and transduces a signal in response to activation of interleukin receptors.
Specifications

Specifications

NP_000206
Cell viability, proliferation and function, pharma and biopharma, protein assays and analysis, target and lead identification and validation
67.4kDa
75% by SDS-PAGE
–80°C
1 Each
JAK3, LJAK, JAKL
JAK3 was pre-diluted in enzyme dilution buffer and assayed in 50mM Tris (pH 7.5), 10mM MgCl2, 0.25mM EGTA, 0.1mM Na3VO4, 5mM β-glycerophosphate, 2.5mM DTT, 0.01% Triton™ X-100, 200μM ATP, 200μg/mL Abl1 peptide substrate (EAIYAAPFAKKK) and trace [32P]-γ-ATP for 10 minutes at 30°C
Kinase and inhibitors
JAK
JAK3 Recombinant Human Protein
Human
0.37mg/mL
3718
JAK3 Recombinant Human Protein
10μg
For research use only. Not for use in diagnostic procedures
Cytoplasmic tyrosine kinase
JAK3 Recombinant Human Protein
Kinase assay
Baculovirus
Amino acids 781-1124
160nmoles of phosphate transferred to Abl1 peptide substrate (EAIYAAPFAKKK) per minute per mg of total protein at 30°C. Activity determined at a final protein concentration of 1.67μg/mL
GST Tag
Documents

For Research Use Only. Not for use in diagnostic procedures.