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JAK2 Recombinant Human Protein DFS Item

JAK2 Recombinant Human Protein

Manufacturer:  Life Technologies LSPV4210

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Catalog No. PV4210



Description

Description

Janus kinase 2 (JAK2) is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways and is mutated in polycythemia vera. This kinase contains the catalytic domain (JH1) of JAK2.
Specifications

Specifications

NP_004963
Cell viability, proliferation and function, pharma and biopharma, protein assays and analysis, target and lead identification and validation
66.6kDa
95% by SDS-PAGE
–80°C
1 Each
JAK2
JAK2 was pre-diluted in enzyme dilution buffer and assayed in 25mM Tris (pH 7.5), 10mM MgCl2, 0.5mM EGTA, 0.5mM Na3VO4, 5mM β-glycerophosphate, 2.5mM DTT, 0.01% Triton™ X-100, 200μM ATP, 200μg/mL Abl1 peptide substrate (EAIYAAPFAKKK) and trace [32P]-γ-ATP for 10 minutes at 30°C
Kinases and inhibitors
aa 809 to 1153 +9
600nmoles of phosphate transferred to Abl1 peptide substrate (EAIYAAPFAKKK) per minute per mg of total protein at 30°C. Activity determined at a final protein concentration of 3.33μg/mL
GST Tag
0.29mg/mL
3439, 3717
JAK2 Recombinant Human Protein
10μg
For research use only. Not for use in diagnostic procedures
Cytoplasmic tyrosine kinases
JAK2 Recombinant Human Protein
Kinase assay
Baculovirus
JAK2 Recombinant Human Protein
Human
Documents

For Research Use Only. Not for use in diagnostic procedures.