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JAK1 Recombinant Human Protein DFS Item

JAK1 Recombinant Human Protein

Manufacturer:  Life Technologies LSPV4774

Catalog No. PV4774



Description

Description

Janus kinase 1 (JAK1), is a protein tyrosine kinase that is involved in the interferon-alpha⁄beta and -gamma signal transduction pathways.
Specifications

Specifications

NP_002218.2
Cell viability, proliferation and function, pharma and biopharma, protein assays and analysis, target and lead identification and validation
60.7kDa
95% by SDS-PAGE
–80°C
1 Each
JAK1, JAK1A, JAK1B
JAK1 was pre-diluted in enzyme dilution buffer and assayed in 25mM Tris (pH 7.5), 10mM MgCl2, 0.5mM EGTA, 0.5mM Na3VO4, 5mM β-glycerophosphate, 2.5mM DTT, 0.01% Triton™ X-100, 100μM ATP, 333.3μg/mL IRS-1 (Y608) peptide substrate (KKHTDDGYMPMSPGVA) and trace [32P]-γ-ATP for 10 minutes at 30°C
Kinase and inhibitors
JAK
JAK1 Recombinant Human Protein
Human
0.16mg/mL
3716
JAK1 Recombinant Human Protein
10μg
For research use only. Not for use in diagnostic procedures
Cytoplasmic tyrosine kinase
JAK1 Recombinant Human Protein
Kinase assay
Baculovirus
Amino acids 866-1154
110nmoles of phosphate transferred to IRS-1 (Y608) peptide substrate (KKHTDDGYMPMSPGVA) per minute per mg of total protein at 30°C. Activity determined at a final protein concentration of 0.833μg/mL
GST Tag
Documents

For Research Use Only. Not for use in diagnostic procedures.