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Jagged 2 Armenian Hamster anti-Mouse, eFluor 660, Clone: HMJ2-1, eBioscience™

Armenian Hamster Monoclonal Antibody

$130.68 - $328.68

Specifications

Antigen Jagged 2
Clone HMJ2-1
Host Species Armenian Hamster
Gene Alias Jag2
Applications Flow Cytometry
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
501124341 Life Technologies
LS50339280
25μg Each for $130.68
501124342 Life Technologies
LS50339282
100μg Each for $328.68
Specifications

Description

This HMJ2-1 monoclonal antibody reacts with mouse Jagged-2, one of five type I transmembrane proteins that serves as a Notch receptor ligand. Upon binding the Notch receptor (e.g., Notch 1-4), Jagged-2 undergoes proteolytic cleavage, first by ADAM-family metalloproteases and then by gamma-secretase. The second cleavage event releases an intracellular fragment whose biological function remains controversial. Jagged-2 is expressed by thymic lymphoid and stromal cells, as well as macrophages and dendritic cells in the spleen.

Note: Staining of endogenous splenic dendritic (CD8+CD11c+) cells could only be consistently confirmed in cells isolated from C57BL/6, but not Balb/c, mice. Other strains have not been tested. The antiobdy has been reported to crossreact to rat and have blocking function.
Description & Specifications

Specifications

Jagged 2
Armenian Hamster
Flow Cytometry
eFluor 660
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
0.2mg/mL
HMJ2-1
Jag2
RUO
Conjugated
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer