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Tocris™ J 147

Neuroprotective and neurotrophic compound; reduces Abeta40 and Abeta42 levels

$205.70 - $862.95

Specifications

Product Type J 147
Inhibitors J 147
Molecular Weight 350.33
Purity >99
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Disclaimers:

For Research Use Only



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
508110R Tocris™
RDS508110
10mg Each for $205.70
508150R Tocris™
RDS508150
50mg Each for $862.95
Specifications

Description

Potent neuroprotective and neurotrophic compound. Protects against neurotoxicity in cortical neurons in vitro (EC50 = 25 - 200nM). Reduces soluble Aβ40 and Aβ42 levels and increases BDNF levels in the hippocampus in vivo. Enhances memory in wild type rats. Prevents memory deficits and rescues cognitive deficits in young and aged transgenic Alzheimer's Disease mice, respectively. Orally active.
  • Chemical Name: 2,2,2-Trifluoroacetic acid 1-(2,4-Dimethylphenyl)-2-[(3-methoxyphenyl)methylene]hydrazide
  • Formula: C18H17F3N2O2
  • CAS Number: 1146963-51-0
  • Solubility: Soluble to 100mM in DMSO and to 100mM in ethanol
  • Purity: >99
Description & Specifications

Specifications

J 147
J 147
350.33
>99