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Alfa Aesar™ Isopropylidene malonate, 98%

Manufacturer:  Alfa Aesar™ A1560336

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Catalog No. AAA1560336



Description

Description

Applications
Isopropylidene malonate is an important reagent in synthetic chemistry and involved in the formation of new C-C bonds, rings, amides, esters, and acids. The presence of carbonyl groups at C-4 and C-6 positions favors the alkylation and acylation reactions due to its acidic nature. It is also employed as an antimicrobial agent. It is used in the preparation of 4-pyridyl-substituted heterocycles, 2-substituted indoles, isofraxidin and macrocyclic beta-keto lactones. Further, it is involved in the Knoevenagel condensation reaction with aldehydes.

Solubility
Soluble in water. Slightly soluble in ethanol and chloroform.

Notes
Store in a cool place. Incompatible with strong oxidizing agents.
Specifications

Specifications

Isopropylidene malonate
500g
C6H8O4
117310
meldrum's acid, isopropylidene malonate, meldrums acid, 1,3-dioxane-4,6-dione, 2,2-dimethyl, sub-isopropyl malonate, 2,2-dimethyl-1,3-dioxan-4,6-dione, cycl-isopropylidene malonate, cyclic isopropylidene malonate, malonic acid cyclic isopropylidene ester, meldrum acid
CC1(OC(=O)CC(=O)O1)C
144.126
144.13
92°C to 96°C
2033-24-1
MFCD00006638
14,5817
GXHFUVWIGNLZSC-UHFFFAOYSA-N
2,2-dimethyl-1,3-dioxane-4,6-dione
16249
98%

Chemical Identifiers

2033-24-1
144.126
GXHFUVWIGNLZSC-UHFFFAOYSA-N
16249
CC1(OC(=O)CC(=O)O1)C
C6H8O4
MFCD00006638
meldrum's acid, isopropylidene malonate, meldrums acid, 1,3-dioxane-4,6-dione, 2,2-dimethyl, sub-isopropyl malonate, 2,2-dimethyl-1,3-dioxan-4,6-dione, cycl-isopropylidene malonate, cyclic isopropylidene malonate, malonic acid cyclic isopropylidene ester, meldrum acid
2,2-dimethyl-1,3-dioxane-4,6-dione
Safety and Handling

Safety and Handling

GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.

GHS P Statement
P261-P280-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapors/spray.
Wear protective gloves/protective clothing/eye protection/face protection.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.

Warning

RTECSNumber : JH0800000

TSCA : TSCA

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