Iodobenzene is used to prepare biphenyl and stilbene. It reacts with magnesium to form the Grignard reagent, a phenylmagnesium iodide used in organic synthesis. It finds application as a solid chlorine source by reacting with chlorine to form a complex, iodobenzene dichloride. It serves as a substrate in Sonogashira reaction which is used to form a carbon-carbon bond between a terminal alkyne and an aryl halide.
Miscible with ethanol, chloroform and ether. Slightly miscible with dimethyl sulfoxide. Immiscible with water.
Light sensitive. Incompatible with magnesium and strong oxidizing agents.
Safety and Handling
GHS H Statement
Harmful if swallowed.
GHS P Statement
Avoid breathing dust/fume/gas/mist/vapors/spray.
Wear protective clothing.
RTECSNumber : DA3390000
TSCA : TSCA