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2-Iodoacetamide, 98%, stab. with ca 5-8% water, Alfa Aesar™

Manufacturer:  Alfa Aesar A1471522

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Catalog No. AAA1471522



Description

Description

Applications
Alkylating agent used in peptide mapping because it covalently binds with the thiols in cysteine to prevent disulfide bond formation2-Iodoacetamide is used as an electrophile for covalent modification of nucleophilic residues on proteins such as cysteine, methionine and histidine. It is used to bind with thiol group of cysteine, thereby it protects the formation disulfide bonds. It is involved as an inhibitor of deubiquitinase enzymes (DUBs). Further, it acts as an alkylating sulfhydryl reagent.

Solubility
Soluble in water, dimethyl formamide and ethanol. Slightly soluble in methanol.

Notes
Store in a cool place. Light and moisture sensitive. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong acids, strong bases, strong oxidizing agents and strong reducing agents.
Specifications

Specifications

2-Iodoacetamide
92°C to 95°C (dried)
stabilized with ≈5 to 8% water
98%, stabilized with ca 5% water
MFCD00008028
1739080
PGLTVOMIXTUURA-UHFFFAOYSA-N
2-iodoacetamide
3727
98%
Characteristic
100g
144-48-9
C2H4INO
UN2811
iodoacetamide, monoiodoacetamide, surauto, acetamide, 2-iodo, 2-iodo-acetamide, usaf d-1, alpha-iodoacetamide, ccris 7710, unii-zrh8m27s79, n-3-methoxy-4-butoxybenzyl thiobarbituric acid
C(C(=O)N)I
184.964
184.96

Chemical Identifiers

144-48-9
184.964
PGLTVOMIXTUURA-UHFFFAOYSA-N
3727
C(C(=O)N)I
C2H4INO
MFCD00008028
iodoacetamide, monoiodoacetamide, surauto, acetamide, 2-iodo, 2-iodo-acetamide, usaf d-1, alpha-iodoacetamide, ccris 7710, unii-zrh8m27s79, n-3-methoxy-4-butoxybenzyl thiobarbituric acid
2-iodoacetamide
Safety and Handling

Safety and Handling

GHS H Statement
H301-H315-H319-H317-H335
Toxic if swallowed.
Causes skin irritation.
Causes serious eye irritation.
May cause an allergic skin reaction.
May cause respiratory irritation.

GHS P Statement
P261-P280-P301+P310-P305+P351+P338-P405-P501a
Avoid breathing dust/fume/gas/mist/vapors/spray.
Wear protective gloves/protective clothing/eye protection/face protection.
IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.

Danger

DOTInformation : Transport Hazard Class: 6.1; Packing Group: III; Proper Shipping Name: TOXIC SOLIDS, ORGANIC, N.O.S.

RTECSNumber : AC4200000

TSCA : TSCA

Recommended Storage : 2° to 8°C

SDS Documents