Please login to your online account to display your discounted pricing

Thermo Scientific™ Lab Vision™ Involucrin Ab-1, Mouse Monoclonal Antibody


Thermo Scientific™ Involucrin Ab-1, Mouse Monoclonal Antibody provides accurate, reproducible results.

Manufacturer: thermo scientific™ lab vision™  MS126P1ABX

 View more versions of this product

Catalog No. MS126P1ABX

  • / Each
 

Description & Specifications

Specifications

Antigen Involucrin Ab-1
Applications Enzyme Linked Immunosorbent Assay
Applications Immunofluorescence
Applications Immunohistochemistry (Paraffin)
Applications Immunoprecipitation
Applications Western Blotting
Classification Monoclonal
Clone SY5
Concentration 1mg/mL
Conjugate Unlabeled
Cross Reactivity Canine
Cross Reactivity Human
Cross Reactivity Non-Human Primate
Cross Reactivity Porcine
Cross Reactivity Rat
Format Concentrated
Formulation Ab without BSA/Azide (Frozen)
Host Species Mouse
Immunogen Human keratinocytes involucrin
Isotype IgG1
Quantity 100µL
Regulatory Status RUO
Research Discipline Cytoskeletal Protein
Type Primary

Thermo Scientific™ Involucrin Ab-1, Mouse Monoclonal Antibody provides accurate, reproducible results. 

Involucrin is expressed in a range of stratified squamous epithelia, including the cornea. In normal epidermis, it is first expressed in the upper spinous layers, and in keratinocyte cultures it is expressed by all cells that have left the basal layer. Involucrin expression is abnormal in squamous cell carcinomas and premalignant lesions, and is reduced in severe dysplasias of the larynx and cervix.

Host Species: Mouse

Clone: SY5

Isotype: IgG1

Species Reactivity: Human, Gorilla, Owl, Monkey, Pig, Dog and Rat. Others not known.

Epitope: Codon 421-568

Immunogen: Human keratinocytes' involucrin

Molecular Weight: 66-170kDa

Positive Control: LS174T cells, Skin

Cellular Localization: Cytoplasmic Ab-1 stains the involucrin in a variety of sizes: 170kDa in MCF-7 cells, a doublet of ∽115kDa and 150kDa in gorilla and owl monkey, 66kDa in dog, and a doublet of 105kDa in pig.

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunofluorescence
  • Immunoprecipitation (Denatured verified)
  • ELISA

Note:

USA: RUO; Int'l: RUO