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Thermo Scientific™ Lab Vision™ Involucrin Ab-1, Mouse Monoclonal Antibody

Thermo Scientific™ Involucrin Ab-1, Mouse Monoclonal Antibody provides accurate, reproducible results.

Manufacturer:  Thermo Scientific™ Lab Vision™ MS126P1ABX

 View more versions of this product

Catalog No. MS126P1ABX


 

Specifications

Description

Thermo Scientific™ Involucrin Ab-1, Mouse Monoclonal Antibody provides accurate, reproducible results. 

Involucrin is expressed in a range of stratified squamous epithelia, including the cornea. In normal epidermis, it is first expressed in the upper spinous layers, and in keratinocyte cultures it is expressed by all cells that have left the basal layer. Involucrin expression is abnormal in squamous cell carcinomas and premalignant lesions, and is reduced in severe dysplasias of the larynx and cervix.

Host Species: Mouse

Clone: SY5

Isotype: IgG1

Species Reactivity: Human, Gorilla, Owl, Monkey, Pig, Dog and Rat. Others not known.

Epitope: Codon 421-568

Immunogen: Human keratinocytes' involucrin

Molecular Weight: 66-170kDa

Positive Control: LS174T cells, Skin

Cellular Localization: Cytoplasmic Ab-1 stains the involucrin in a variety of sizes: 170kDa in MCF-7 cells, a doublet of ∽115kDa and 150kDa in gorilla and owl monkey, 66kDa in dog, and a doublet of 105kDa in pig.

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunofluorescence
  • Immunoprecipitation (Denatured verified)
  • ELISA

Note:

USA: RUO; Int'l: RUO

Description & Specifications

Specifications

Involucrin Ab-1
Monoclonal
1mg/mL
Canine,Human,Non-Human Primate,Porcine,Rat
Ab without BSA/Azide (Frozen)
Human keratinocytes involucrin
100μL
Cytoskeletal Protein
Monoclonal
Enzyme Linked Immunosorbent Assay,Immunofluorescence,Immunohistochemistry (Paraffin),Immunoprecipitation,Western Blotting
SY5
Unlabeled
Concentrated
Murine
IgG1
RUO
Primary
Canine,Human,Non-human Primate,Porcine,Rat