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Integrin Beta 7 Rat anti-Human, Mouse, PE-Cy7, Clone: FIB504, eBioscience™

Rat Monoclonal Antibody

$157.08 - $394.68

Specifications

Antigen Integrin Beta 7
Clone FIB504
Host Species Rat
Gene Alias Integrin b7, ITGB7
Applications Flow Cytometry
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
501123398 Life Technologies
LS25586741
25 Tests Each for $157.08
501129068 Life Technologies
LS25586742
100 Tests Each for $394.68
Specifications

Description

The FIB504 monoclonal antibody reacts with human and mouse integrin beta 7. Integrin beta 7 is a 130 kD glycoprotein which associates with integrin alpha 4 (CD49d) to form the alpha 4 beta 7 integrin LPAM-1, expressed on intraepithelial lymphocytes. It also associates with alpha E (CD103) to form the alpha E beta 7 integrin HML-1, expressed on T cells adjacent to mucosal epithelium and intraepithelial lymphocytes. Main ligands for integrin alpha 4 beta 7 include VCAM-1 (CD106), MAdCAM-1 and fibronectin, while the main ligand of integrin alpha E beta 7 is E-cadherin (CD324). Integrin beta 7 plays an important role in the adhesion of leukocytes to endothelial cells promoting the transmigration of leukocytes to extravascular spaces during the inflammatory response. The FIB504 antibody has been reported to have blocking activity.
Description & Specifications

Specifications

Integrin Beta 7
Rat
Flow Cytometry
PE-Cy7
Store at 2-8°C. Do not freeze. Light-sensitive material. This tandem dye is sensitive to photo-induced oxidation. Protect this vial from light during storage
Monoclonal
5μL (0.125μg)/test
FIB504
Integrin b7, ITGB7
RUO
Conjugated
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer