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Integrin Beta 7 Rat anti-Human, Mouse, FITC, Clone: FIB504, eBioscience™

Rat Monoclonal Antibody

$143.55 - $288.55

Specifications

Antigen Integrin Beta 7
Clone FIB504
Host Species Rat
Gene Alias Integrin b7, ITGB7
Species Reactivity Human, Mouse
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
509885 Life Technologies
LS11586741
25 Tests Each for $143.55
509886 Life Technologies
LS11586742
100 Tests Each for $288.55
Specifications

Description

The FIB504 monoclonal antibody reacts with human and mouse integrin beta 7. Integrin beta 7 is a 130 kD glycoprotein which associates with integrin alpha 4 (CD49d) to form the alpha 4 beta 7 integrin LPAM-1, expressed on intraepithelial lymphocytes. It also associates with alpha E (CD103) to form the alpha E beta 7 integrin HML-1, expressed on T cells adjacent to mucosal epithelium and intraepithelial lymphocytes. Main ligands for integrin alpha 4 beta 7 include VCAM-1 (CD106), MAdCAM-1 and fibronectin, while the main ligand of integrin alpha E beta 7 is E-cadherin (CD324). Integrin beta 7 plays an important role in the adhesion of leukocytes to endothelial cells promoting the transmigration of leukocytes to extravascular spaces during the inflammatory response. The FIB504 antibody has been reported to have blocking activity.
Description & Specifications

Specifications

Integrin Beta 7
Rat
Human, Mouse
RUO
Conjugated
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
FIB504
Integrin b7, ITGB7
Flow Cytometry
FITC
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
5μL (0.125μg)/test