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Integrin alpha 4 beta 7 (LPAM-1) Rat anti-Mouse, PE, Clone: DATK32 (DATK-32), eBioscience™

Rat Monoclonal Antibody

$147.84 - $381.48

Specifications

Antigen Integrin alpha 4 beta 7 (LPAM-1)
Clone DATK32 (DATK-32)
Host Species Rat
Species Reactivity Mouse
Applications Flow Cytometry
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
5010950 Life Technologies
LS12588781
50μg Each for $147.84
5010951 Life Technologies
LS12588782
100μg Each for $267.96
5010952 Life Technologies
LS12588783
200μg Each for $381.48
Specifications

Description

The DATK32 monoclonal antibody binds to a combinatorial epitope of mouse LPAM-1 (alpha 4/ beta 7), which is a heterodimer of the the 154kDa alpha 4 subunit and the 130kDa beta 7 subunit. In mouse, the beta 7 subunit is found on the majority of mature lymphocytes and a small population of thymocytes and bone marrow cells. LPAM-1 is an integrin involved in the transendothelial migration of lymphocytes across high endothelial venules (HEV), and is know to bind several ligands including MAdCAM-1, VCAM-1 and fibronectin. Binding of the DATK32 monoclonal antibody has been shown to induce aggregation of the CD8+ T cell lymphoma TK1, and block LPAM-1-mediated cell adhesion.
Description & Specifications

Specifications

Integrin alpha 4 beta 7 (LPAM-1)
Rat
Flow Cytometry
PE
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
0.2mg/mL
DATK32 (DATK-32)
Mouse
RUO
Conjugated
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer