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Integrin alpha 4 beta 7 (LPAM-1) Rat anti-Mouse, Clone: DATK32 (DATK-32), eBioscience™

Rat Monoclonal Antibody

$77.88 - $302.28

Specifications

Antigen Integrin alpha 4 beta 7 (LPAM-1)
Clone DATK32 (DATK-32)
Host Species Rat
Applications Flow Cytometry,Functional Assay
Regulatory Status RUO
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
5013278 Life Technologies
LS14588781
50μg Each for $77.88
5013280 Life Technologies
LS14588785
500μg Each for $302.28
5013279 Life Technologies
LS14588782
100μg Each for $117.48
Specifications

Description

The DATK32 monoclonal antibody binds to a combinatorial epitope of mouse LPAM-1 (α4β7), which is a heterodimer of the the 154kDa α4 subunit and the 130kDa β7 subunit. In mouse, the β7 subunit is found on the majority of mature lymphocytes and a small population of thymocytes and bone marrow cells. LPAM-1 is an integrin involved in the transendothelial migration of lymphocytes across high endothelial venules (HEV), and is know to bind several ligands including MAdCAM-1, VCAM-1 and fibronectin. Binding of the DATK32 monoclonal antibody has been shown to induce aggregation of the CD8+ T cell lymphoma TK1, and block LPAM-1-mediated cell adhesion.
Description & Specifications

Specifications

Integrin alpha 4 beta 7 (LPAM-1)
Rat
RUO
Purified
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
DATK32 (DATK-32)
Flow Cytometry,Functional Assay
Unlabeled
Store at 2-8°C.
Monoclonal
0.5mg/mL