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Integrin alpha 4 beta 7 (LPAM-1) Rat anti-Mouse, Biotin, Clone: DATK32 (DATK-32), eBioscience™

Rat Monoclonal Antibody

$105.60 - $376.20

Specifications

Antigen Integrin alpha 4 beta 7 (LPAM-1)
Clone DATK32 (DATK-32)
Host Species Rat
Species Reactivity Mouse
Applications Flow Cytometry
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
5011994 Life Technologies
LS13588781
50μg Each for $105.60
5011995 Life Technologies
LS13588782
100μg Each for $161.04
5011996 Life Technologies
LS13588785
500μg Each for $376.20
Specifications

Description

The DATK32 monoclonal antibody binds to a combinatorial epitope of mouse LPAM-1 (α4β7), which is a heterodimer of the the 154kDa α4 subunit and the 130kDa β7 subunit. In mouse, the β7 subunit is found on the majority of mature lymphocytes and a small population of thymocytes and bone marrow cells. LPAM-1 is an integrin involved in the transendothelial migration of lymphocytes across high endothelial venules (HEV), and is know to bind several ligands including MAdCAM-1, VCAM-1 and fibronectin. Binding of the DATK32 monoclonal antibody has been shown to induce aggregation of the CD8+ T cell lymphoma TK1, and block LPAM-1-mediated cell adhesion.
Description & Specifications

Specifications

Integrin alpha 4 beta 7 (LPAM-1)
Rat
Flow Cytometry
Biotin
Store at 2-8°C. Do not freeze.
Monoclonal
0.5mg/mL
DATK32 (DATK-32)
Mouse
RUO
Conjugated
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer