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Thermo Scientific™ Lab Vision™ Insulin Receptor (β -Subunit) Ab-5, Mouse Monoclonal Antibody


Recommended for a variety of molecular biology techniques, Thermo Scientific™ Insulin Receptor (β-Subunit) Ab-5, Mouse Monoclonal Antibody provides accurate, reproducible results.

Manufacturer: thermo scientific™ lab vision™  MS635P1ABX

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Catalog No. MS635P1ABX

  • / Each
 

Description & Specifications

Specifications

Antigen Insulin Receptor (beta-Subunit) Ab-5
Applications Immunoprecipitation
Classification Monoclonal
Clone CT-1
Concentration 1mg/mL
Conjugate Unlabeled
Cross Reactivity Human
Cross Reactivity Mouse
Cross Reactivity Rat
Format Concentrated
Host Species Mouse
Immunogen A 15-mer synthetic peptide corresponding to aa Tyr-KKNGRILTLPRSNPS from the C-terminal of human insulin receptor Beta-subunit
Isotype IgG2a kappa
Quantity 100µL
Regulatory Status RUO
Research Discipline Steroids Hormones and Growth Factors
Type Primary

Recommended for a variety of molecular biology techniques, Thermo Scientific™ Insulin Receptor (β-Subunit) Ab-5, Mouse Monoclonal Antibody provides accurate, reproducible results.

The human insulin receptor is a heterotetrameric membrane glycoprotein consisting of disulfide-linked subunits in a Β-α-α-Β configuration. The Β-subunit (95kDa) possesses a single transmembrane domain with tyrosine kinase acivity, whereas the α-subunit (135kDa) is completely extracellular.

Host Species: Mouse

Clone: CT-1

Isotype: IgG1/κ

Species Reactivity: Human, Mouse and Rat.

Epitope: aa-GRVLTLPRS- within the C-terminus

Immunogen: A 15-mer synthetic peptide corresponding to aa Tyr-KKNGRILTLPRSNPS from the C-terminal of human insulin receptor β-subunit

Molecular Weight: 95kDa

Positive Control: IM-9 lymphocyte cells

Cellular Localization: Membrane Ab-5 reacts with autophosphorylated and unoccupied receptors as well as the receptor-insulin complex. Ab-5 does not affect insulin-stimulated autophosphorylation.

Recommended for:

  • Immunoprecipitation
  • Affinity Purification (With peptide elution)
  • ELISA (As capture antibody only)
  • Tyrosine Kinase Assay (Ab-mediated capture on microplates)

Note:

USA: RUO; Int'l: RUO