Please login to your online account to display your discounted pricing

Thermo Scientific™ Lab Vision™ Insulin Receptor (β -Subunit) Ab-5, Mouse Monoclonal Antibody


Recommended for a variety of molecular biology techniques, Thermo Scientific™ Insulin Receptor (β-Subunit) Ab-5, Mouse Monoclonal Antibody provides accurate, reproducible results.

Manufacturer: thermo scientific™ lab vision™  MS635P1ABX

 View more versions of this product

Catalog No. MS635P1ABX

  • / Each
 

Description & Specifications

Specifications

Antigen Insulin Receptor (beta-Subunit) Ab-5
Applications Immunoprecipitation
Classification Monoclonal
Clone CT-1
Concentration 1mg/mL
Conjugate Unlabeled
Cross Reactivity Human
Cross Reactivity Mouse
Cross Reactivity Rat
Format Concentrated
Host Species Murine
Immunogen A 15-mer synthetic peptide corresponding to aa Tyr-KKNGRILTLPRSNPS from the C-terminal of human insulin receptor Beta-subunit
Isotype IgG2a kappa
Quantity 100μL
Regulatory Status RUO
Research Discipline Steroids Hormones and Growth Factors
Type Primary
Monoclonal or Polyclonal Monoclonal
Target Species Human
Target Species Murine
Target Species Rat

Recommended for a variety of molecular biology techniques, Thermo Scientific™ Insulin Receptor (β-Subunit) Ab-5, Mouse Monoclonal Antibody provides accurate, reproducible results.

The human insulin receptor is a heterotetrameric membrane glycoprotein consisting of disulfide-linked subunits in a Β-α-α-Β configuration. The Β-subunit (95kDa) possesses a single transmembrane domain with tyrosine kinase acivity, whereas the α-subunit (135kDa) is completely extracellular.

Host Species: Mouse

Clone: CT-1

Isotype: IgG1/κ

Species Reactivity: Human, Mouse and Rat.

Epitope: aa-GRVLTLPRS- within the C-terminus

Immunogen: A 15-mer synthetic peptide corresponding to aa Tyr-KKNGRILTLPRSNPS from the C-terminal of human insulin receptor β-subunit

Molecular Weight: 95kDa

Positive Control: IM-9 lymphocyte cells

Cellular Localization: Membrane Ab-5 reacts with autophosphorylated and unoccupied receptors as well as the receptor-insulin complex. Ab-5 does not affect insulin-stimulated autophosphorylation.

Recommended for:

  • Immunoprecipitation
  • Affinity Purification (With peptide elution)
  • ELISA (As capture antibody only)
  • Tyrosine Kinase Assay (Ab-mediated capture on microplates)

Note:

USA: RUO; Int'l: RUO