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Thermo Scientific™ Insulin Receptor (α -Subunit) Ab-3, Mouse Monoclonal Antibody


Recommended for a variety of molecular biology techniques, Thermo Scientific™ Insulin Receptor (α-Subunit) Ab-3, Mouse Monoclonal Antibody provides accurate, reproducible results.

Manufacturer: thermo scientific™  MS633P1ABX

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Catalog No. MS633P1ABX

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Description & Specifications

Specifications

Host Species Mouse
Antigen Insulin Receptor (alpha-Subunit) Ab-3
Immunogen IM-9 lymphocytes followed by purified insulin receptor
Regulatory Status RUO
Clone 47-9
Cross Reactivity Bovine
Cross Reactivity Human
Cross Reactivity Porcine
Cross Reactivity Sheep
Format Concentrated
Isotype IgG1
Quantity 100µL
Research Discipline Steroids Hormones and Growth Factors
Type Primary
Classification Monoclonal
Concentration 1mg/mL
Conjugate Unlabeled

Recommended for a variety of molecular biology techniques, Thermo Scientific™ Insulin Receptor (α-Subunit) Ab-3, Mouse Monoclonal Antibody provides accurate, reproducible results.

The human insulin receptor is a heterotetrameric membrane glycoprotein consisting of disulfide-linked subunits in a Β-α-α-Β configuration. The Β-subunit (95kDa) possesses a single transmembrane domain with tyrosine kinase activity, whereas the α-subunit (135kDa) is completely extracellular.

Host Species: Mouse

Clone: 47-9

Isotype: IgG1

Species Reactivity: Human, Cow, Pig and Sheep. Weakly reacts with Rabbit. Does not react with mouse and rat. Others not known.

Epitope: Exon 7/8

Immunogen: IM-9 lymphocytes followed by purified insulin receptor

Molecular Weight: 135kDa

Positive Control: IM-9 lymphocyte cells

Cellular Localization: Membrane Ab-3 inhibits (>90%) insulin binding and Blocks insulin action.

Recommended for:

  • Western Blotting (Not suitable)
  • Immunoprecipitation (Not suitable)
  • Antagonist (Blocks insulin action)
  • Completely Inhibits (>90%) Insulin Binding

Note:

USA: RUO; Int'l: RUO