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Thermo Scientific™ Insulin Receptor (α -Subunit) Ab-3, Mouse Monoclonal Antibody


Recommended for a variety of molecular biology techniques, Thermo Scientific™ Insulin Receptor (α-Subunit) Ab-3, Mouse Monoclonal Antibody provides accurate, reproducible results.

Manufacturer: thermo scientific™  MS633P1ABX

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Catalog No. MS633P1ABX

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Description & Specifications

Specifications

Antigen Insulin Receptor (alpha-Subunit) Ab-3
Classification Monoclonal
Clone 47-9
Concentration 1mg/mL
Conjugate Unlabeled
Cross Reactivity Bovine
Cross Reactivity Human
Cross Reactivity Porcine
Cross Reactivity Sheep
Format Concentrated
Host Species Mouse
Immunogen IM-9 lymphocytes followed by purified insulin receptor
Isotype IgG1
Quantity 100µL
Regulatory Status RUO
Research Discipline Steroids Hormones and Growth Factors
Type Primary

Recommended for a variety of molecular biology techniques, Thermo Scientific™ Insulin Receptor (α-Subunit) Ab-3, Mouse Monoclonal Antibody provides accurate, reproducible results.

The human insulin receptor is a heterotetrameric membrane glycoprotein consisting of disulfide-linked subunits in a Β-α-α-Β configuration. The Β-subunit (95kDa) possesses a single transmembrane domain with tyrosine kinase activity, whereas the α-subunit (135kDa) is completely extracellular.

Host Species: Mouse

Clone: 47-9

Isotype: IgG1

Species Reactivity: Human, Cow, Pig and Sheep. Weakly reacts with Rabbit. Does not react with mouse and rat. Others not known.

Epitope: Exon 7/8

Immunogen: IM-9 lymphocytes followed by purified insulin receptor

Molecular Weight: 135kDa

Positive Control: IM-9 lymphocyte cells

Cellular Localization: Membrane Ab-3 inhibits (>90%) insulin binding and Blocks insulin action.

Recommended for:

  • Western Blotting (Not suitable)
  • Immunoprecipitation (Not suitable)
  • Antagonist (Blocks insulin action)
  • Completely Inhibits (>90%) Insulin Binding

Note:

USA: RUO; Int'l: RUO