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INSR Recombinant Human Protein DFS Item

INSR Recombinant Human Protein

Manufacturer:  Life Technologies LSPV3781

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Catalog No. PV3781



Description

Description

INSR is a receptor tyrosine kinase. Binding of insulin to the extracellular domain of INSR stimulates glucose uptake.
Specifications

Specifications

NP_000199
Cell structure, pharma and biopharma, protein assays and analysis, target and lead identification and validation
71.5kDa
90% by SDS-PAGE
–80°C
1 Each
INSR
INSR was pre-diluted in enzyme dilution buffer and assayed in 25mM Tris (pH 7.5), 10mM MgCl2, 0.5mM EGTA, 0.5mM Na3VO4, 5mM β-glycerophosphate, 2.5mM DTT, 0.01% Triton™ X-100, 200μM ATP, 200μg/mL AXLtide peptide substrate (KKSRGDYMTMQIG) and trace [32P]-γ-ATP for 10 minutes at 30°C
Kinase and inhibitors
Insulin & IGF receptor
INSR Recombinant Human Protein
Human
0.37mg/mL
3643
INSR Recombinant Human Protein
10μg
For research use only. Not for use in diagnostic procedures
Receptor tyrosine kinases
INSR Recombinant Human Protein
Kinase assay
Baculovirus
Amino acids 1011-1382
6820nmoles of phosphate transferred to AXLtide peptide substrate (KKSRGDYMTMQIG) per minute per mg of total protein at 30°C. Activity determined at a final protein concentration of 1.67μg/mL
GST Tag
Documents

For Research Use Only. Not for use in diagnostic procedures.