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Alfa Aesar™ Indole-3-carbonitrile, 98%

$49.14 - $620.91

Chemical Identifiers

Chemical Name or Material Indole-3-carbonitrile
CAS 5457-28-3
Molecular Formula C9H6N2
Formula Weight 142.16g/mol
MDL Number MFCD00022717
Beilstein 120888
Synonym 3-Cyanoindole
View More Specs
Products
Catalog Number Mfr. No. Quantity Price Quantity    

AAA1604103

 
alfa aesar™
A16041-03
1g Each for $49.14

AAA1604106

 
alfa aesar™
A16041-06
5g Each for $198.51

AAA1604114

 
alfa aesar™
A16041-14
25g Each for $620.91
Description & Specifications

Specifications

Melting Point 177° to 182°C
Quantity 1g
Odor Odorless
Chemical Name or Material Indole-3-carbonitrile
CAS 5457-28-3
Assay 98%
Molecular Formula C9H6N2
Formula Weight 142.16g/mol
MDL Number MFCD00022717
Beilstein 120888
Synonym 3-Cyanoindole
Health Hazard 1 Warning
Health Hazard 2 GHS H Statement
H302-H315-H319-H335
Harmful if swallowed.
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
Health Hazard 3 GHS P Statement
P261-P280-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapors/spray.
Wear protective gloves/protective clothing/eye protection/face protection.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.

Applications
Indole-3-carbonitrile is used as a synthesis reagent for preparation of 4-substituted β-lactams, biologically active indoles, inhibitors of glycogen synthase kinase 3β (GSK-3), indole fragments as inosine monophosphate dehydrogenase (IMPDH) inhibitors and HIV-1 integrase inhibitors. It is also used as a reactant for intramolecular oxidative C-H coupling reactions with applications in medium-ring synthesis techniques and for preparation of tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles as potential anticancer immunomodulators.

Solubility
Insoluble in water.

Notes
Keep container tightly sealed. Store in cool, dry conditions in well sealed containers. Incompatible with oxidizing agents. It is sensitive to light.

Safety and Handling

Warning

GHS P Statement
P261-P280-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapors/spray.
Wear protective gloves/protective clothing/eye protection/face protection.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.

GHS H Statement
H302-H315-H319-H335
Harmful if swallowed.
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.