Imiquimod, TLR7 ligand is an imidazoquinoline amine analog to guanosine. As a synthetic molecule of the Imidazoquinoline family, it has potent immunostimulatory activity. Imiquimod has been shown to activate only TLR7, this activation is MyD88 dependant and leads to the induction of the transcription factor NF-kB.
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.