Imidazole is used as a buffer in the range of pH 6.2-7.8. It is also an histamine antagonist. It acts as a chelator and forms complexes with various divalent cations. It is used as a corrosion inhibitor on certain transition metals such as copper. Its derivatives, like polybenzimidazole (PBI), act as fire retardants. It finds application in photography and electronics. Imidazole salts are used as ionic liquids and precursors to stable carbenes. Imidazole derivatives like ketoconazole, miconazole and clotrimazole are involved in the treatment of various systemic fungal infections. It is a part of the theophylline molecule, present in tea leaves and coffee beans, which stimulates the central nervous system.
Miscible with water, ethanol, ether, acetone, chloroform, pyridine and methanol. Slightly miscible with benzene and petroleum ether.
Incompatible with acids, acid anhydrides and strong oxidizing agents.
|88° to 92°C|
Safety and Handling
GHS H Statement
Causes severe skin burns and eye damage.
Causes serious eye damage.
Harmful if swallowed.
GHS P Statement
Do not breathe dust/fume/gas/mist/vapours/spray.
IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.
DOTInformation : Transport Hazard Class: 8; Packing Group: III; Proper Shipping Name: CORROSIVE SOLIDS, TOXIC, N.O.S.
RTECSNumber : NI3325000
TSCA : TSCA