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IL-8 (CXCL8) Mouse anti-Human, Clone: N11, eBioscience™

Mouse Monoclonal Antibody

$187.05 - $390.05

Specifications

Antigen IL-8 (CXCL8)
Clone N11
Host Species Mouse
Gene Alias Interleukin-8, IL8
Species Reactivity Human
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5013658

 
affymetrix
14-7189-80
25μg Each for $187.05

5013659

 
affymetrix
14-7189-82
100μg Each for $390.05
Description & Specifications

Specifications

Antigen IL-8 (CXCL8)
Clone N11
Host Species Mouse
Gene Alias Interleukin-8, IL8
Species Reactivity Human
Applications Western Blotting
Regulatory Status RUO
Conjugate Unlabeled
Format Purified
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.5mg/mL

The monoclonal antibody N11 reacts specifically with the 77 amino acid form of IL-8 (IL-877, IL-8(1-77), CXCL877) and does not react with the more common 72 amino acid form. Frequently referred to as “endothelial” IL-8, the 77 amino acid form is secreted in cultured leukocytes. The 72 amino acid form is the result of efficient cleavage of an N-terminal pentamer from IL-877 after secretion. IL-8 is a C-X-C chemokine with potency in neutrophil chemotaxis and activation. IL-877 has decreased chemotactic activity when compared to IL-872, but has other specific pro-apoptotic and tumor cell chemotactic activities. IL-877 has recently been shown to be the major isoform present in premature neonates due to deficiency in serum protease activity that is not seen in term neonates.