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IL-38 Mouse anti-Human, Clone: H127C, eBioscience™

Mouse Monoclonal Antibody

$158.05 - $419.05

Specifications

Antigen IL-38
Clone H127C
Host Species Mouse
Gene Alias Interleukin-38, IL-1F10
Species Reactivity Human
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

501122728

 
affymetrix
14738580
25μg Each for $158.05

501122729

 
affymetrix
14738582
100μg Each for $419.05
Description & Specifications

Specifications

Antigen IL-38
Clone H127C
Host Species Mouse
Gene Alias Interleukin-38, IL-1F10
Species Reactivity Human
Applications Enzyme Linked Immunosorbent Assay
Applications Flow Cytometry
Applications Immunohistochemistry
Applications Immunohistochemistry (Formalin/Paraffin)
Applications Immunoprecipitation
Applications Western Blotting
Regulatory Status RUO
Conjugate Unlabeled
Format Purified
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.5mg/mL

The monoclonal antibody H127C recognizes human IL-38. IL-38 is a member of the Interleukin-1 family (IL-1F) and shares homology with IL-1R antagonist (IL-1Ra) and IL-36R antagonist (IL-36Ra). IL-38 is expressed mostly in the skin and proliferating B cells of the tonsil and is also present at low levels in the heart and placenta. IL-38 functions as an anti-inflammatory cytokine that inhibits IL-36 by binding to IL-36R and also inhibits the production of IL-17 and IL-22. Gene polymorphisms of IL-38 are associated with psoriatic arthritis, ankylosing spondylitis, and heart disease.