Please login to your online account to display your discounted pricing

IL-33R (ST2) Rat anti-Mouse, PerCP-eFluor 710, Clone: RMST2-2, eBioscience™

Rat Monoclonal Antibody

$187.05 - $477.05

Specifications

Antigen IL-33R (ST2)
Clone RMST2-2
Host Species Rat
Gene Alias IL-1RL1, IL-1R4, T1
Species Reactivity Mouse
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

501123946

 
affymetrix
46933582
100μg Each for $477.05

501128826

 
affymetrix
46-9335-80
25μg Each for $187.05
Description & Specifications

Specifications

Antigen IL-33R (ST2)
Clone RMST2-2
Host Species Rat
Gene Alias IL-1RL1, IL-1R4, T1
Species Reactivity Mouse
Applications Flow Cytometry
Regulatory Status RUO
Conjugate PerCP-eFluor 710
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material. This tandem dye is sensitive to photo-induced oxidation. Protect this vial from light during storage
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.2mg/mL

The RMST2-2 monoclonal antibody reacts with ST2, also known as IL-33 receptor (IL-33R) or interleukin 1 receptor-like 1. ST2 is a member of the IL-1 receptor family. In the membrane-bound form, it consists of three extra-cellular immunoglobulin domains and an intracellular toll-interleukin-1 receptor domain. ST2 forms a dimer with IL-1R accessory protein in a ligand-dependent manner. The IL-33/ST2 interaction induces the production of TH2 cytokines. ST2 also has a soluble isoform lacking transmembrane and intracellular toll-interleukin-1 receptor domains. It is believed that the soluble form functions as a decoy receptor that can block membrane bound IL-33/ST2 interaction. ST2 is expressed by TH2 lymphocytes, mast cells, eosinophils, basophils, innate lymphocytes, smooth muscle cells, and endothelial cells and is involved in host defense, allergy, and inflammation. The IL-33/ST2 interaction has also been shown to be atheroprotective.