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IL-22 Rat anti-Mouse, PE, Clone: 1H8PWSR, eBioscience™

Rat Monoclonal Antibody

$419.05 - $578.55

Specifications

Antigen IL-22
Clone 1H8PWSR
Host Species Rat
Gene Alias Interleukin-22
Species Reactivity Mouse
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
5011179 Life Technologies
LS12722182
100μg Each for $578.55
501128898 Life Technologies
LS12722180
25μg Each for $419.05
Specifications

Description

The 1H8PWSR monoclonal antibody reacts with mouse interleukin(IL)-22. IL-22 is a 20kDa member of the IL-10 cytokine family that is secreted primarily by Th17, NK cells, and some other T cells. In in vitro Th17 cultures, induction of IL-22 expression is greater in response to IL-23 than IL-6 or TGF-ß, suggesting that this cytokine may be secreted by more fully differentiated Th17 cells in vivo. A heterodimer consisting of IL-10R2 and IL-22R1 serves as the receptor for IL-22. Th17-secreted IL-22 binds to the IL-22 receptor complexon target cells to induce the expression of anti-microbial peptides ß-defensin-2 and ß-defensin-3. Recently, it was demonstrated that IL-22 is able to protect hosts against bacterial infections of the lungs and gut.
Description & Specifications

Specifications

IL-22
Rat
Mouse
RUO
Conjugated
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
1H8PWSR
Interleukin-22
Flow Cytometry (Intracellular Staining)
PE
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
0.2mg/mL