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IL-22 Rat anti-Human, Mouse, Clone: IL22JOP, Functional Grade, eBioscience™

Rat Monoclonal Antibody, Functional Grade

$143.88 - $368.28

Specifications

Antigen IL-22
Clone IL22JOP
Host Species Rat
Gene Alias Interleukin-22, IL22
Applications Cytokine Neutralization
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
5014736 Life Technologies
LS16722282
100μg Each for $143.88
5014737 Life Technologies
LS16722285
500μg Each for $368.28
Specifications

Description

The monoclonal antibody IL22JOP reacts with and inhibits the bioactivity of human and mouse IL-22. IL-22 is a 20kDa member of the IL-10 cytokine family that is secreted primarily by Th17 cells, NK cells, and other T cells. Compared to IL-6 or TGF beta, IL-23 can induce greater levels of IL-22 in in vitro-differentiated Th17 cells. This observation suggests that IL-22 may be secreted by more fully differentiated Th17 cells in vivo. Recently, it was demonstrated that IL-22 could protect hosts from bacterial infection of the lungs and gut. Moreover, it has been reported that anti-CD3/CD28-induced production of IL-22 by PBMCs was elevated significantly in asthma patients compared to control patients. Flow cytometric analysis also showed that the frequencies of IL-17+IL-22+ CD4 T cells were increased in PBMCs from patients with ankylosing spondylitis and rheumatoid arthritis.
Description & Specifications

Specifications

IL-22
Rat
Cytokine Neutralization
Unlabeled
Store at 2-8°C.
Monoclonal
1mg/mL
IL22JOP
Interleukin-22, IL22
RUO
Purified
Primary
aqueous buffer, no sodium azide