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IL-20 Receptor 2 Rat anti-Human, Mouse, Clone: 20RNTC, eBioscience™

Rat Monoclonal Antibody

$158.05 - $332.05

Specifications

Antigen IL-20 Receptor 2
Clone 20RNTC
Host Species Rat
Gene Alias Interleukin-20 Receptor
Species Reactivity Human, Mouse
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5012839

 
affymetrix
14-1206-82
100μg Each for $332.05

5012838

 
affymetrix
14120680
25μg Each for $158.05
Description & Specifications

Specifications

Antigen IL-20 Receptor 2
Clone 20RNTC
Host Species Rat
Gene Alias Interleukin-20 Receptor
Species Reactivity Human, Mouse
Applications Flow Cytometry
Applications Immunocytochemistry
Applications Western Blotting
Regulatory Status RUO
Conjugate Unlabeled
Format Purified
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.5mg/mL

This 20RNTC monoclonal antibody recognizes mouse and human IL-20R2 (interleukin-20 receptor 2, IL-20Rb) in either of its two heterodimeric complexes formed by pairing with IL-20R1 or IL-22R1. IL-20R2 belongs to the class II cytokine receptor family that shares a characteristic pattern of cysteine, proline and tryptophan residues in the extracellular domain. IL-20R2 paired with IL-20R1 forms a receptor that binds IL-20, IL-19, or IL-24. IL-20R2 paired with IL22R1 forms a receptor that binds IL-20 or IL-24. The IL-20R complex signals primarily via the JAK-STAT pathway. IL-20R2 is found predominantly on cells of epithelial origin such as gut and skin and can be upregulated during inflammation. Immunofluorescent staining of A375 cells reveals a punctate staining pattern at the cell membrane, as well as diffuse, cytoplasmic staining that is likely associated with protein synthesis and transport in the endoplasmic reticulum and golgi.