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IL-17AF Rat anti-Mouse, PE, Clone: B8KN8R, eBioscience™

Rat Monoclonal Antibody

$216.05 - $535.05

Specifications

Antigen IL-17AF
Clone B8KN8R
Host Species Rat
Gene Alias Interleukin-17AF
Species Reactivity Mouse
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
501122422 Life Technologies
LS12917180
25μg Each for $216.05
501122423 Life Technologies
LS12917182
100μg Each for $535.05
Specifications

Description

The B8KN8R monoclonal antibody reacts with mouse interleukin (IL)-17AF heterodimer. This antibody specifically reacts with this heterodimer and has no reactivity for IL-17A or IL-17F homodimers. IL-17A and IL-17F are well-characterized homodimeric cytokines secreted by T helper 17 (Th17) cells, gamma-delta T cells and several subsets of innate lymphoid cells. Somewhat less appreciated, IL-17A and IL-17F subunits can also form the heterodimer, IL-17AF. Together, these three dimers signal through the IL-17RA/IL-17RC receptor complex to mediate immune responses at mucosal interfaces and are found at lesion sites in inflammatory bowel disease, asthma, atopic dermatitis and rheumatoid arthritis.
Description & Specifications

Specifications

IL-17AF
Rat
Mouse
RUO
Conjugated
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
B8KN8R
Interleukin-17AF
Flow Cytometry (Intracellular Staining)
PE
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
0.2mg/mL