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IL-17AF Mouse anti-Human, PE, Clone: 20LJS09, eBioscience™

Mouse Monoclonal Antibody

$216.05 - $535.05

Specifications

Antigen IL-17AF
Clone 20LJS09
Host Species Mouse
Gene Alias Interleukin-17AF
Species Reactivity Human
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

50245536

 
affymetrix
12917941
25 tests Each for $216.05

50245537

 
affymetrix
12917942
100 tests Each for $535.05
Description & Specifications

Specifications

Antigen IL-17AF
Clone 20LJS09
Host Species Mouse
Gene Alias Interleukin-17AF
Species Reactivity Human
Applications Flow Cytometry (Intracellular Staining)
Regulatory Status RUO
Conjugate PE
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 5μL (0.5μg)/test

The 20LJS09 monoclonal antibody reacts with human interleukin (IL)-17AF heterodimer. This antibody specifically reacts with this heterodimer and has no reactivity for IL-17A or IL-17F homodimers. IL-17A and IL-17F are well-characterized homodimeric cytokines secreted by T helper 17 (Th17) cells, gamma-delta T cells and several subsets of innate lymphoid cells. Somewhat less appreciated, IL-17A and IL-17F subunits can also form the heterodimer, IL-17AF. Together, these three dimers signal through the IL-17RA/IL-17RC receptor complex to mediate immune responses at mucosal interfaces and are found at lesion sites in inflammatory bowel disease, asthma, atopic dermatitis and rheumatoid arthritis.