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IL-13 Rat anti-Mouse, Clone: eBio1316H, Functional Grade, eBioscience™

Rat Monoclonal Antibody, Functional Grade

$129.05 - $419.05

Specifications

Antigen IL-13
Clone eBio1316H
Host Species Rat
Gene Alias Interleukin-13
Species Reactivity Mouse
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
5014724 Life Technologies
LS16713585
500μg Each for $419.05
5014723 Life Technologies
LS16713581
50μg Each for $129.05
Specifications

Description

The eBio1316H antibody reacts with mouse IL-13. The eBio1316H antibody is a neutralizing antibody. Mouse interleukin-13 (IL-13), originally designated p600, is a 11.6kDa protein secreted by activated T helper cells, CD8+ T cells, and NK cells. IL-13 was originally identified in 1989 through differential hybridization of cDNA libraries prepared from T helper 1 and T helper 2 cells. IL-13 contains four cysteine residues, which form two intramolecular disulfide bonds. IL-13 shares many activities with IL-4; this relates to a requirement for IL-4Ralpha chain for signal transduction. The biological activities of IL-13 include suppression of macrophage cytotoxic activity, upregulation of IL-1RA expression, and suppression of inflammatory cytokine expression. IL-13 induces CD23 expression on B cells and enhances CD72, and expression of class II MHC gene products. Mouse IL-13 does not display the activities on T cells and B cell stimulatory effects which IL-4 exhibits. Mouse IL-13 is active on human and mouse cells.
Description & Specifications

Specifications

IL-13
Rat
Mouse
RUO
Purified
Primary
aqueous buffer, no sodium azide
eBio1316H
Interleukin-13
Cytokine Neutralization
Unlabeled
Store at 2-8°C.
Monoclonal
1mg/mL