Please login to your online account to display your discounted pricing

IL-13 Rat anti-Mouse, Clone: eBio1316H, Functional Grade, eBioscience™

Rat Monoclonal Antibody, Functional Grade

$129.05 - $419.05

Specifications

Antigen IL-13
Clone eBio1316H
Host Species Rat
Gene Alias Interleukin-13
Species Reactivity Mouse
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5014724

 
affymetrix
16713585
500μg Each for $419.05

5014723

 
affymetrix
16-7135-81
50μg Each for $129.05
Description & Specifications

Specifications

Antigen IL-13
Clone eBio1316H
Host Species Rat
Gene Alias Interleukin-13
Species Reactivity Mouse
Applications Cytokine Neutralization
Regulatory Status RUO
Conjugate Unlabeled
Format Purified
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, no sodium azide
Concentration 1mg/mL

The eBio1316H antibody reacts with mouse IL-13. The eBio1316H antibody is a neutralizing antibody. Mouse interleukin-13 (IL-13), originally designated p600, is a 11.6kDa protein secreted by activated T helper cells, CD8+ T cells, and NK cells. IL-13 was originally identified in 1989 through differential hybridization of cDNA libraries prepared from T helper 1 and T helper 2 cells. IL-13 contains four cysteine residues, which form two intramolecular disulfide bonds. IL-13 shares many activities with IL-4; this relates to a requirement for IL-4Ralpha chain for signal transduction. The biological activities of IL-13 include suppression of macrophage cytotoxic activity, upregulation of IL-1RA expression, and suppression of inflammatory cytokine expression. IL-13 induces CD23 expression on B cells and enhances CD72, and expression of class II MHC gene products. Mouse IL-13 does not display the activities on T cells and B cell stimulatory effects which IL-4 exhibits. Mouse IL-13 is active on human and mouse cells.