Please login to your online account to display your discounted pricing

IL-12 Rat anti-Mouse, Clone: C18.2, eBioscience™

Rat Monoclonal Antibody

$129.05 - $346.55

Specifications

Antigen IL-12
Clone C18.2
Host Species Rat
Gene Alias Interleukin-12
Species Reactivity Mouse
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5013634

 
affymetrix
14-7122-81
50μg Each for $129.05

5013635

 
affymetrix
14712285
500μg Each for $346.55
Description & Specifications

Specifications

Antigen IL-12
Clone C18.2
Host Species Rat
Gene Alias Interleukin-12
Species Reactivity Mouse
Applications Cytokine Neutralization
Applications ELISA Capture
Regulatory Status RUO
Conjugate Unlabeled
Format Purified
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.5mg/mL

The C18.2 antibody reacts with the p35 subunit of mouse interleukin-12 (IL-12). Interleukin-12 (IL-12) is a heterodimeric 70 kD (p70) cytokine composed of two covalently linked, glycosylated chains, 40kD (p40) and 35-kD (p35). IL-12 is mainly produced by monocytes, macrophages, and dendritic cells in response to bacterial products such as lipopolysaccharides (LPS), to intracellular pathogens or upon interaction with activated T cells. IL-12 was originally discovered because of its ability to induce interferon-gamma (IFN-g) production, cell proliferation, and cytotoxicity mediated by natural killer cells and T cells. It is now established that IL-12 also plays a key role in the development of Th1 responses, leading to IFN-g and IL-2 production. These cytokines can in turn promote T-cell responses and macrophage activation.